Since being discovered in 1993, microRNAs have gone on to win a Nobel Prize in Physiology or Medicine, thanks to private sector uptake with the COVID-19 vaccines that saved the world during the pandemic that emerged from Wuhan, China in early 2020. 

Errors in the manufacture of over 1,000 microRNAs can put us at risk for developmental disorders, cancer, or neurodegenerative disease and a new study looks at a molecular machine called Microprocessor (MP), which trims longer molecules called primary microRNAs (pri-miRNAs) - without cutting other kinds of RNA that resemble pri-miRNAs.

No one likes getting a needle but most want a vaccine. A new paper shows progress for messenger RNA (mRNA), that can be sprayed and inhaled thanks to improved lipid-polymer nanoparticle technology for holding mRNA that is stable when nebulized and successfully delivers aerosols, liquid droplets, in mouse lungs. 

A mouse study means this is only EXPLORATORY but the authors of the paper, including scientists from oRNA Therapeutics (RNA medicine) and Moderna (mRNA medicine), have filed for a patent while they get ready to see about human trials. 

Attorney Robert F. Kennedy Jr. and his US followers over the last 25 years have staunchly opposed vaccines, latching on to any claim that they cause autism or should be available for lawsuits even if they harm no one.

They really won't like a new experimental vaccine for Smallpox and Monkeypox that avoids the side effects of a current live virus version while not needing two doses, as the replication-deficient virus version does. It uses the horsepox virus as a protective agent to confer the safety of a multi-dose vaccine in a single shot. 

General medicine, routine visits and such, have gradually gone from M.D.s to including Osteopaths and now Physicians Assistants with no decline in quality, and Large Language Models, colloquially called "Artificial Intelligence", like ChatGPT can assist at very low cost.

Cigarettes are the top lifestyle risk factor for getting cancer, though alcohol and obesity have begun to close the gap as awareness of the risks of cigarettes, coupled with more nicotine smoking cessation and harm reduction tools, have caused cigarette use to decline.

Even if you get cancer, quitting smoking improves outcomes. 

When Senator Elizabeth Warren had her claims of native ancestry debunked by DNA testing, it was a warning shot to everyone who identifies that way - don't take a test. Most native Americans had long said that anyway, they knew how biology worked better Washington DC staffers. After five generations there is a chance there will be no evidence of an ancestor so natives have long told their communities not to participate. If there are only a few hundred in a database, the database is meaningless and natives tribes can continue their 'we agree you are and you agree you are native' policy rather than having evidence.