A new paper in Free Radical Biology and Medicine
suggests that a diet low in vitamin D causes damage to the brain.
In addition to being essential for maintaining bone health, the new evidence found that vitamin D serves important roles in other organs and tissue, including the brain. The study showed that middle-aged rats that were fed a diet low in vitamin D for several months developed free radical damage to the brain, and many different brain proteins were damaged as identified by redox proteomics.
These rats also showed a significant decrease in cognitive performance on tests of learning and memory.
"Given that vitamin D deficiency is especially widespread among the elderly, we investigated how during aging from middle-age to old-age how low vitamin D affected the oxidative status of the brain," said lead author on the paper Allan Butterfield, professor in the University of Kentucky Department of Chemistry. "Adequate vitamin D serum levels are necessary to prevent free radical damage in brain and subsequent deleterious consequences."
Previously, low levels of vitamin D have been associated with Alzheimer's disease, and it's also been linked to the development of certain cancers and heart disease. In both the developed world and in areas of economic hardship where food intake is not always the most nutritious, vitamin D levels in humans are often low, particularly in the elderly population.
Butterfield recommends persons consult their physicians to have their vitamin D levels determined, and if low that they eat foods rich in vitamin D, take vitamin D supplements, and/or get at least 10-15 minutes of sun exposure each day to ensure that vitamin D levels are normalized and remain so to help protect the brain.