Cells are filled with membrane-bound organelles like the nucleus, mitochondria and endoplasmic reticula. Over the years, scientists have made much progress in understanding the biomolecular details of how these organelles function within cells, but understanding the actual physical forces that maintain the structures of these organelles' membranes continues to be a challenge. 

Now, UCLA Henry Samueli School of Engineering and Applied Science researcher William Klug and colleagues from the California Institute of Technology and the Whitehead Institute for Biomedical Research in Massachusetts have devised a mathematical procedure for accurately predicting the three-dimensional forces involved in creating and maintaining certain organelle membranes. 

Eating saturated fats from butter, cream and meat, as well as trans fats found in hydrogenated oils can boost our risk of cardiovascular disease, while consuming mono-unsaturated fat can be good for our heart.

Yet what's the effect of all these fats on our weight? Are some better than others?

"Research on animals and some clinical trials show that not all fats have the same effect on weight," says Nadiah Moussavi, a Master's student from the Université de Montréal Department of Nutrition. "Few epidemiological studies exist on the subject and the results of those are contradictory."

New data from The Kinsey Institute at Indiana University demonstrate that many women think condoms undermine sexual pleasure, but those who use both hormonal contraception and condoms report higher overall sexual satisfaction.

The study authors suggest that this inconsistency reflects how women think about their contraceptive method when asked questions about two different aspects of sexuality -- sexual enjoyment and overall sexual satisfaction.

When considering overall sexual satisfaction, which goes beyond the immediate sexual moment and includes factors such as sexual self-esteem and relationship satisfaction, women who used both condoms and hormonal methods reported the highest levels of sexual satisfaction.

Having kids believe there's a jolly man in a red suit who visits on Christmas Eve doesn't turn out to be very detrimental, according to a new analysis by Serge Larivée, although some parents can feel they're outright lying to their children and a small percentage of kids feel that way toward their parents. 

"When they learn the truth, children accept the rules of the game and even go along with their parents in having younger children believe in Santa," says Larivée, a psycho-education professor at the Université de Montréal. "It becomes a rite of passage in that they know they are no longer babies."

Every living thing is composed of cells and, via receptor proteins on their outer surface, cells communicate with each other and with the outside world. Receptors are found on skin cells (pain and pressure receptors, for example) as well as on the cells of other tissues and organs.

A new genome-wide study examines genetic variants associated with nine metabolic traits and is the first to draw out novel variants from a population unselected for current disease. The traits are indicators for common disease such as cardiovascular disease, type 2 diabetes, blood pressure, inflammation and lipid levels.

Cohorts are followed throughout their lives, gathering lifelong information about their health: these data will help researchers to dissect the complex causes of common disease, whether genetic or environmental. The current study might indicate genetic variants that influence early development of disease, informing public health measures.