COLUMBIA, South Carolina, December 2 /PRNewswire/ --

- Semantic Search and Knowledge Discovery Software Company Recognized for Innovation in Eighth Annual EC100 List

Collexis Holdings, Inc. (OTC Bulletin Board: CLXS), a leading developer of semantic search and knowledge discovery software, announced today that it has been named by EContent magazine as one of the 100 Companies that Matter Most in the Digital Content Industry. The list, compiled annually by EContent, recognizes companies in a variety of categories in the digital content industry and reinforces the importance of digital content as a resource that should be maximized by organizations.

We are proud to be recognized as part of the EContent 100, said Bill Kirkland, chief executive officer of Collexis. It's truly an honor to be included among industry forerunners like Apple, IBM and Microsoft and our dedicated team strives to constantly innovate and excel in this dynamic field.

EC100, now in its eighth year, is an annually updated list that recognizes the continued expertise or renewed strength of some of the industry's leaders, as well as innovation of newcomers to the field. Selected by fourteen judges with experience ranging from publishing and content management to online network analysis, Collexis joins the ranks of other global content providers including Thomson Reuters, Reed Elsevier and many others.

We are proud of this list and of the companies on it, said Michelle Manafy, EContent editor-in-chief. Members of the EContent 100 List are the companies empowering the content that fuels business today and we hope that our readers find the list as valuable as we did the process of creating it.

About EContent

EContent is dedicated to one of the most essential commodities any business has to offer -- content. While the digital era has provided businesses with unprecedented access to content, it has also created an exponentially increasing need to manage, store, and deliver that content in ways that are efficient, effective, and affordable. And with this steady rise in digital content challenges, EContent magazine is there to help guide professionals with sound advice and breaking news. EContent is the most respected source for information about the digital content industry. The magazine has a mission to clearly identify and explain emerging digital content trends, strategies, and resources that will help readers navigate the content maze and find a clear path to profits and improved business processes.

EContent delivers essential research, reporting, news, and analysis of content related issues. It is essential reading for executives and professionals involved in content creation, management, acquisition, organization, and distribution in both commercial and enterprise environments. EContent is the premier publication for the digital content industry. (www.econtentmag.com)

About Collexis Holdings, Inc.

Collexis Holdings, Inc., a leading developer of semantic search and knowledge discovery software is headquartered in Columbia, South Carolina (USA) with major operations in Cincinnati, Ohio, Geldermalsen, the Netherlands and Cologne, Germany. Collexis now offers the world's first pre-populated scientific social network for life science researchers, www.biomedexperts.com. Collexis' proprietary technology builds conceptual profiles of text, called Fingerprints, from documents, Websites, emails and other digitized content and matches them with a comprehensive list of pre-defined Fingerprinted concepts to make research results more relevant and efficient. This matching of concepts eliminates the ambiguity and lack of priority associated with word searches. The results are often described as finding needles in many haystacks. Through this novel approach, Collexis can build unique applications to search, index and aggregate information as well as prioritize, trend and predict data based on sources in multiple industries without the limitations of language or dialect. Collexis' current clients in the public, private and academic sectors include the Mayo Clinic; Johns Hopkins University; Dana-Farber Cancer Institute, the University of California, San Francisco; the University of South Carolina; Erasmus University Library; Bristol-Myers Squibb; Lockheed Martin; the World Health Organization; Wellcome Trust; the National Institutes of Health; and the U.S. Department of Defense. Shares of Collexis common stock are traded under the symbol CLXS on the OTC Bulletin Board (OTC BB). For more information, visit www.collexis.com.

Forward-Looking Statements

Some of the statements made in this press release may constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements are based on management's current expectations and include known and unknown risks, uncertainties and other factors, many of which the company is unable to predict or control, that may cause the company's actual results or performance to differ materially from any future results or performance expressed or implied by such forward-looking statements. These risks and uncertainties are in addition to other factors detailed from time to time in the company's filings with the SEC, including the section entitled Risk Factors in its transition report on Form 10-KSB for the period ended June 30, 2008. The company cautions investors that any forward-looking statements made by the company are not necessarily indicative of future performance. The company is not responsible for updating the information contained in this press release beyond the published date, or for changes made to this document by wire services or Internet services.

Stephanie Jones of Chernoff Newman, Office +1-803-233-2432, stephanie.jones@cnsg.com; or Darrell W. Gunter, EVP-CMO, Collexis Holdings, Inc., Mobile +1-973-454-3475, Office +1-803-727-1113, gunter@collexis.com