Research conducted by scientists at the University of York has revealed how recreational ketamine abuse damages the bladder.

In two studies, one of which is published today, the team shows how ketamine present in urine causes damage to the epithelial lining of the bladder, allowing urine to penetrate into underlying tissues which causes inflammation and extreme pain. In some cases this pain can be so extreme that patients need to have their bladder removed (cystectomy).

BOSTON -Approximately one out of five hospitalized adults and one out of three hospitalized children worldwide experience acute kidney injury, the sudden loss of kidney function. Many different factors, including surgery, chemotherapy or shock, can lead to acute kidney injury, but exactly why the kidneys are so vulnerable to these and other stressors has not been well understood.

A recent analysis of popular music reveals that while older age and aging are represented both negatively and positively in music lyrics, negative representations predominate.

Most of the music texts were generated from a young person's perspective and their imaginings of old age.

While negative and positive emotions can influence health and well-being, further research is needed to explore what impact negative texts in popular music may have on older individuals.

The human brain has a prodigious demand for energy -- 20 to 30% of the body's energy budget. In the course of normal aging, in people with neurodegenerative diseases or mental disorders, or in periods of physiological stress, the supply of sugars to the brain may be reduced. This leads to a reduction in the brain's energy reserves, which in turn can lead to cognitive decline and loss of memory.

But new research on mice shows that the brain's energy reserves can be increased with a daily dose of pyruvate, a small energy-rich molecule that sits at the hub of most of the energy pathways inside the cell. These results need to be replicated in human subjects, but could ultimately lead to clinical applications.

New research shows that, as paint dries, small particles team-up to push away large ones
This newly discovered physical mechanism separates particles according to size, creating 'self-layering' coatings
Could be used to improve the performance of a range of everyday goods, made by industries from beauty to agriculture.

New research published today in the journal Physical Review Letters has described a new physical mechanism that separates particles according to their size during the drying of wet coatings. The discovery could help improve the performance of a wide variety of everyday goods, from paint to sunscreen.

Researchers from The University of Texas Medical Branch at Galveston have found that women who take the birth control pill, which lessen and stabilize estrogen levels, were less likely to suffer serious knee injuries. The findings are currently available in Medicine & Science in Sports & Exercise, the official journal of the American College of Sports Medicine.

On an African plateau surrounded by flat-topped trees as far as the eye could see, wind whistled through the acacia thorns like someone blowing across a bottle. Kathleen Rudolph was more concerned with the ants raining down on her from the trees. The hat, long sleeves and garden gloves the University of Florida researcher wore for protection didn't help.

The acacia ants she studies, Crematogaster mimosae, use their fearsome bite to defend their host trees against large animals such as elephants and giraffes that eat the trees' leaves. Even elephants' thick skin can't protect them from the ants, which bite them inside their trunks.

"They really seem to have a knack for finding your soft tissue," Rudolph said. "It's a nasty business."

Psychologists overuse terms like narcissist and sociopath as much as they do declaring everyone they dislike has Asperger's, but they get one thing right - if you have to deal with such people, you are better off online than in person. 

A team pf psychologists says that traditionally successful manipulators who are classified as what they like to try and deem the Dark Triad (DT)--people with narcissistic, psychopathic or Machiavellian tendencies--don't send very compelling online messages.

Patients with a rare, genetic form of diabetes often are misdiagnosed as having type 2 diabetes because the two share symptoms.

But new research at Washington University School of Medicine in St. Louis suggests that treating such patients with therapies designed for type 2 diabetes is potentially harmful and that treatment guidelines need to change. The underlying problems in patients with the genetic form of the disease -- called maturity-onset diabetes of the young (MODY1) -- are very different from those in type 2 diabetes. And treating MODY1 patients with drugs for type 2 diabetes appears to lead to destruction of insulin-secreting beta cells that regulate blood sugar, the scientists found.

A team of scientists including a Smithsonian Tropical Research Institute (STRI) research associate announced the discovery of a new species of pale-gold colored frog from the cloud forests of the high Andes in Colombia. Its name, Pristimantis dorado, commemorates both its color (dorado means 'golden' in Spanish) and El Dorado, a mythical city of gold eagerly sought for centuries by Spanish conquistadores in South America.

"The Spaniards assumed Colombia's wealth was its gold, but today we understand that the real riches of the country lie in its biodiversity," said Andrew Crawford, a STRI research associate and faculty member at the Universidad de Los Andes.