Researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration,

Inhibitors of the enzyme are being developed as a new anti-cancer target.

Aged and damaged cells frequently undergo a form of proliferation arrest called cellular senescence. These fading cells increase in human tissues with aging and are thought to contribute to age-related increases in both cancer and inflammation. The secretion of such inflammatory compounds as cytokines, growth factors, and proteases is called the senescence-associated secretory phenotype, or SASP.

I have often argued that the pro-life movement has a disconnect about actual life when it comes to science. I don't mean about the health issues of abortion or birth control, I mean about saving babies using science. They seem to think science should only help after a baby is born, exactly the opposite of the argument they make about the beginning of life during abortion debates.

Doctors typically prescribe several drugs to patients with mental health conditions in order to treat the various symptoms. For example, a person with bipolar disorder may be prescribed one drug to treat mania and another to treat depression. But there’s limited evidence on how combinations of drugs interact, or how diet and nutrition influence their effects.

The term "schizophrenia," with its connotation of hopeless chronic brain disease, should be dropped and replaced with something like "psychosis spectrum syndrome," argues Professor Jim van Os at Maastricht University Medical Centre in The BMJ.

Pharmaceutical companies take a lot of cultural heat for high prices, politicians routinely criticize them to score political points, but at least they did real discovery. One out of 5,000 candidates will make it to market, and then it has to be successfully promoted to make back costs that routinely run into the billions of dollars.

Generic companies, on the other hand, get a free pass. They do no work, they just start manufacturing after the real work has been done and the patent expires. Yet the cost savings generic drugs were supposed to bring has not really come to pass. Companies only take up the profitable ones and when a company does try to make a boutique compound profitable, they are criticized for price gouging.

Cluttered and chaotic environments can cause stress, which can lead us to grab more of the indulgent snacks-- twice as many cookies according to this new study!

Conducted at the Cornell Food and Brand Lab and published in Environment and Behavior, the study shows that cluttered kitchens are caloric kitchens. When stressed out females were asked to wait for another person in a messy kitchen -- with newspapers on the table, dishes in the sink, and the phone ringing - they ate twice as many cookies compared to women in the same kitchen when it was organized and quiet. In total they ate 65 more calories more in 10 minutes time.

With the attacks in Paris and in California recently, all linked to Muslim terrorists, where is the line between being factual about who is committing terrorist acts and fueling anti-Muslim sentiment?

Craig Anderson, Distinguished Professor of psychology at Iowa State University, and colleagues think they can find out, by surveying college students.

According to their results, published in the journal Communication Research, there is a link between negative media stories of Muslims and support for military action and restrictions against Muslims. And since conservatives in America are mostly likely to be strong on topics like crime and military defense, they say it was entirely predictable that GOP candidates would take strong stands against terrorism. 

MIAMI--A University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science-led study shows that the North Atlantic absorbed 50 percent more man-made carbon dioxide over the last decade, compared to the previous decade. The findings show the impact that the burning of fossil fuels have had on the world's oceans in just 10 years.

Taking benzodiazepines (widely used drugs to treat anxiety and insomnia) is not associated with an increased dementia risk in older adults, finds a study published by The BMJ today.

These results do not support a direct (causal) association between benzodiazepine use and dementia, say the researchers. However, healthcare providers are still advised to avoid benzodiazepines in older adults to prevent important adverse health outcomes.

Benzodiazepines are widely prescribed among older adults to manage sleep, anxiety and depressive disorders. Some studies have suggested that benzodiazepine use could be associated with an increased risk of dementia, but results are conflicting.

The system that awards national and academic honors to doctors is called into question by a senior doctor writing in The BMJ this week.

Consultant cardiologist, Peter Wilmshurst, tells the story of Anjan Kumar Banerjee, a surgeon who spent the years 2002 to 2008 erased from the medical register for serious professional misconduct related to research fraud, financial misconduct, and substandard care.

Yet in 2014 he was awarded an MBE "for services to patient safety."