AMSTERDAM, May 28 /PRNewswire/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, announced today that the European Medicines Agency has granted Orphan Drug Designation to AMT's gene therapy product AMT-021 for the treatment of acute intermittent porphyria (AIP).

VIB (the Flanders Institute for Biotechnology) researchers linked to K.U.Leuven and Harvard University say they have shown that stretches of DNA previously believed to be useless 'junk' DNA play a vital role in the evolution of our genome. Their findings were that unstable pieces of junk DNA help tuning gene activity and enable organisms to quickly adapt to changes in their environments.

Junk DNA in two paragraphs

"Most people do not realize that all our genes only comprise about 3% of the total human genome. The rest is basically one large black box,"  says Kevin Verstrepen, heading the research team. "Why do we have this DNA, what is it doing?"

Oxidative stress has been linked to aging, cancer and other diseases in humans. Paradoxically, researchers have suggested that small exposure to oxidative conditions may actually offer protection from acute doses. Now, scientists at the University of California, San Diego, have discovered the gene responsible for this effect. Their study, published in PLoS Genetics on May 29, explains the underlying mechanism of the process that prevents cellular damage by reactive oxygen species (ROS).

Scientists at the University of Leeds say they have uncovered a previously unknown giant volcanic eruption.   And it's no ordinary eruption, they say - it led to global mass extinction 260 million years ago. 

The eruption in the Emeishan province of south-west China unleashed around half a million cubic kilometres of lava, covering an area 5 times the size of Wales, and wiping out marine life around the world.

Even if we don't always notice, our brain is constantly distracted with 'noise' - unimportant messages that are filtered out.   

When we pay attention, our neurons begin firing in harmony and a study in the May 29 issue of Science lays out what researchers say is the likely brain center that serves as the conductor of our neural chorus.  MIT neuroscientists say that neurons in the prefrontal cortex, the brain's planning center, fire in unison and send signals to the visual cortex to do the same, generating high-frequency waves that oscillate between these distant brain regions like a vibrating spring. These waves, also known as gamma oscillations, have long been associated with cognitive states like attention, learning, and consciousness.

Biomedical engineers at Boston University have taught bacteria how to count.  The researchers have wired a new sequence of genes that allow the microbes to count discrete events, opening the door for a host of potential applications, which could include drug delivery and sensing environmental hazards. 

The young but burgeoning field of synthetic biology addresses biological research questions with an engineering approach. Researchers design and build networks of genes, splicing them into bacterial genomes to run specific tasks or manufacture desired molecules – a process akin to installing biological computer software. Though the field is rapidly advancing, the gene-based tools available to synthetic biologists remain limited. 

How common is scientific misconduct?   It's a tough question to answer.   Scandals like Hwang Woo-Suk's faked stem-cell lines or Jon Sudbø's made-up cancer trials have demonstrated that fraudulent research is easy to publish, even in the most prestigious print journals, but are they deviations of a few "bad apples" or evidence that a great deal more is never discovered?  The actual numbers are a matter of dispute.

In a PLoS ONE meta-analysis of surveys questioning scientists about their misbehaviors, Daniele Fanelli of the University of Edinburgh, a PhD in the behavior and genetics of Malaysian and Panamanian tropical wasps, suggests that altering or making up data is more frequent than previously estimated and might be particularly high in medical research.

Researchers using data from NASA's THEMIS mission have pinpointed the impact epicenter of an earthbound space storm as it crashes into the atmosphere - and given an advance warning of its arrival. The team's study reveals that magnetic blast waves can be used to pinpoint and predict the location where space storms dissipate their massive amounts of energy. These storms can dump the equivalent of 50 gigawatts of power, or the output of 10 of the world's largest power stations, into Earth's atmosphere.

The joint Japan-U.S. Suzaku mission is providing new insight into how assemblages of thousands of galaxies pull themselves together and, for the first time, Suzaku has detected X-ray-emitting gas at a cluster's outskirts, where a billion-year plunge to the center begins.

Suzaku ("red bird of the south") was launched on July 10, 2005. The observatory was developed at the Japanese Institute of Space and Astronautical Science (ISAS), which is part of the Japan Aerospace Exploration Agency (JAXA), in collaboration with NASA and other Japanese and U.S. institutions.

A team of physicists and engineers have demonstrated all-fibre quantum logic, where single photons are generated and used to perform the contolled-NOT quantum logic gate in optical fibers with high fidelity.

The only quantum technology in practical use today is quantum cryptography and is currently limited in the distance over which secure communication may occur.

More sophisticated quantum networks will require multiple nodes with the ability to implement small-scale quantum processing in order to increase the range of quantum communications. Such networks will rely on optical fibre links, making fibre-based photon generation and information processing of key technological importance.