Montréal, October 2, 2014 – Scientists at the IRCM discovered a mechanism that promotes the progression of medulloblastoma, the most common brain tumour found in children. The team, led by Frédéric Charron, PhD, found that a protein known as Sonic Hedgehog induces DNA damage, which causes the cancer to develop. This important breakthrough will be published in the October 13 issue of the prestigious scientific journal Developmental Cell. The editors also selected the article to be featured on the journal's cover.

Sonic Hedgehog belongs to a family of proteins that gives cells the information needed for the embryo to develop properly. It also plays a significant role in tumorigenesis, the process that transforms normal cells into cancer cells.

CHAMPAIGN, Ill. — The big-headed ant (Pheidole megacephala) is considered one of the world's worst invasive ant species. As the name implies, its colonies include soldier ants with disproportionately large heads. Their giant, muscle-bound noggins power their biting parts, the mandibles, which they use to attack other ants and cut up prey. In a new study, researchers report that big-headed ant colonies produce larger soldiers when they encounter other ants that know how to fight back.

The new findings appear in the Biological Journal of the Linnean Society.

Scientists at the University of California, Santa Cruz, using a new wildlife tracking collar they developed, were able to continuously monitor the movements of mountain lions in the wild and determine how much energy the big cats use to stalk, pounce, and overpower their prey.

The research team's findings, published October 3 in Science, help explain why most cats use a "stalk and pounce" hunting strategy. The new "SMART" wildlife collar--equipped with GPS, accelerometers, and other high-tech features--tells researchers not just where an animal is but what it is doing and how much its activities "cost" in terms of energy expenditure.

A new device invented at The Ohio State University is the world's first hybrid solar generator and battery - it solves the problem of finicky solar power generation by having the storage built in.

The key is a mesh solar panel, which allows air to enter the battery, and a special process for transferring electrons between the solar panel and the battery electrode. Inside the device, light and oxygen enable different parts of the chemical reactions that charge the battery.

As the Supreme Court of the United States begins its fall 2014 session this month, it faces decisions on several "blockbuster" cases, including freedom of speech, religious freedoms in prison, pregnancy discrimination and a possible decision on gay marriage.

Just don't expect any of these decisions until next June, just before the court's session ends.
New research from the Washington University in St. Louis School of Law finds big, or "blockbuster," cases are disproportionately decided at the end of June, just before the court's summer recess.

"We knew that more than 30 percent of the court's decisions are issued in June and more than half of those in the last week," said Lee Epstein, PhD, the Ethan A. H. Shepley Distinguished University Professor.

Zoonosis—transmission of infections from other vertebrates to humans—causes regular and sometimes serious disease outbreaks. Bats are a well-known vertebrate reservoir of viruses like rabies and Ebola. Recent discovery of sequences in bats that are resemble influenza virus genes raised the question of whether bat flu viruses exist and could pose a threat to humans. A study published on October 2nd in PLOS Pathogens addresses this question based on detailed molecular and virological characterization.

The yeast has not been gene modified by the researchers; rather, they have used adaptive laboratory evolution to produce it. The method allows new characteristics to be produced without knowing which mutations are required to achieve them.

Three yeast cultivations were subjected to a temperature of about 40 degrees. After just over three months, when over 300 generations had passed, the yeast suddenly started to grow effectively in all three cultivations. The researchers analysed the genetic structure and metabolism in three yeast strains from each cultivation. They concluded that while several different mutations had occurred in the strains, all the strains had the mutation that produced fecosterol.

In June of this year, Facebook provoked a widespread public outcry after it became known that it had tried to manipulate the emotions of nearly 700,000 of its users as part of a social “experiment.”

By Mark Blumberg, University of Iowa; Alexandre Tiriac, University of Iowa, and Carlos del Rio Bermudez, University of Iowa

By Nicholas Ellaby, University of Liverpool

From eyes to the gap between the toes, we are covered in bacterial colonies.

Between 500 and 1000 unique species live in our gut alone. We provide an ideal environment for bacteria: warmth, moisture, nutrients and protection.