A team of researchers at the University of Alberta, including a scientist at the University of Pennsylvania, have discovered a gene that is able to block HIV, and thought to in turn prevent the onset of AIDS.
Dr. Stephen Barr, a researcher in the Department of Medical Microbiology & Immunology at the U of A, says his team identified a human gene called TRIM22 that can block HIV infection in a cell culture by preventing the assembly of the virus.
Barr says “interestingly, when we prevent cells from turning on TRIM22, the normal interferon response (a natural defense produced by our cells to fight infection by viruses such as HIV) is useless at blocking HIV infection.