A songbirds' vocal muscles work like those of human speakers and singers, finds a new study. The research on Bengalese finches showed that each of their vocal muscles can change its function to help produce different parameters of sounds, in a manner similar to that of a trained opera singer.

Pitch, for example, is important to songbird vocalization, but there is no single muscle devoted to controlling it. They don't just contract one muscle to change pitch, they have to activate a lot of different muscles in concert, and these changes are different for different vocalizations. Depending on what syllable the bird is singing, a particular muscle might increase pitch or decrease pitch.

ST. LOUIS - Opioids may cause short-term improvement in mood, but long-term use imposes risk of new-onset depression, a Saint Louis University study shows.

For half a century, cancer researchers have struggled with a confusing paradox: If cancer is caused by the occurrence and accumulation of cancer-causing (oncogenic) mutations over time, young children should get less cancer since they have fewer mutations.

So why do young children have a higher incidence of leukemia than teenagers and young adults? 

NEW YORK, NY (Jan. 6, 2016) -- A new study conducted at Columbia University Medical Center (CUMC) has revealed some of the underlying mechanisms that may increase the risk of heart disease in people with sleep apnea. The study also found that statins -- the cholesterol-lowering medications commonly prescribed to combat heart disease -- may help reverse this process.

The study was published in the Jan. 6, 2016 online edition of Science Translational Medicine.

The compound CGP3466B, already proven nontoxic for people, may effectively and rapidly treat depression, according to results of a study in mice.

The Johns Hopkins Medicine neuroscientists who conducted the research say that the compound -- previously shown to block cocaine craving in the brains of rodents -- delivers antidepressant effects to mice within hours instead of weeks or months, like currently available antidepressants. The results of the study will be summarized Jan. 12 online in the journal Molecular Psychiatry.

Psychiatrists investigating depression have been energized in recent years by reports of rapid, successful treatment with drugs that interfere with the brain chemical glutamate, such as the anesthetic ketamine.

New research from Emory University School of Medicine is providing hints as to which forms of depression may respond best to drugs that target glutamate.

The findings are scheduled for publication online on January 12 in Molecular Psychiatry.

Depressed patients with signs of systemic inflammation have elevated levels of glutamate in regions of the brain that are important for motivation, the researchers have found.

Life expectancy at birth is about six years shorter for White males than White females. This gap is about eight years for Blacks. Given the close correlation between declining health and early death, older males are effectively on average several years more aged than females. The detailed shapes of statistics could conceivably not support such ‘hyper-aging’, or it could conceivably result in only a few months of hyper-aging. The ‘Hyperaged Men Description’ is however strongly confirmed by the shape of for example Europe’s population pyramid. There is no far earlier onset of males dying, or any features that could point toward more exotic, perhaps purely biological explanations.

The Romans created a clear line between Iron Age and modern sanitation and hygiene. They built public multi-seat latrines with washing facilities and sewerage systems, they piped drinking water from aqueducts and heated public baths for washing.

To augment that, they developed laws designed to keep their towns free of excrement and rubbish.

But it may not have helped when it came to putting a stop to intestinal parasites such as whipworm, roundworm and Entamoeba histolytica dysentery, according to a journal in the journal Parasitology.

The coffee berry borer (Hypothenemus hampei) is a plague that affects coffee crops. It has a detoxification system based on microbial communities so it can perform its life cycle in the plant while exposed to high levels of caffeine.

In human terms, the caffeine is equivalent to 500 espressos , which would kill a person.

"The aim was to study which are they and how they are associated with the digestive tract of the insect. For the study we took samples of insects from different locations like Hawaii, Indonesia, Puerto Rico, Mexico, Kenya, India and Guatemala," Javier A. Ceja Navarro of Berkeley National Laboratory told Investigación y Desarrollo.

Over the last few decades, medicine has witnessed a sea change in attitudes toward chronic pain, and particularly toward opioids. While these changes were intended to bring relief to many, they have also fed an epidemic of prescription opioid and heroin abuse.

Curbing abuse is a challenge spilling over into the 2016 political campaigns. Amid calls for better addiction treatment and prescription monitoring, it might be time for doctors to rethink how to treat chronic pain.