Surgeons from UC Davis Medical Center say they have demonstrated that artificial muscles can restore the ability of patients with facial paralysis to blink, a development that could potentially  prevent corneal ulcers and the blindness that usually follows. Detailed in the January-February issue of the Archives of Facial Plastic Surgery, the development could benefit the thousands of people each year who no longer are able to close their eyelids due to combat-related injuries, stroke, nerve injury or facial surgery.

In addition, the technique, which uses a combination of electrode leads and silicon polymers, could be used to develop synthetic muscles to control other parts of the body. The new

Reporting in the Journal of Biological Chemistry, an international team of researchers has determined the structure of 14α-Demethylase (14DM), an enzyme essential to the survival of the protozoan parasites that cause sleeping sickness, Chagas disease and leishmaniasis. They say this new information provides the first up-close look at the busy enzyme and, perhaps more importantly, shows how one compound in particular prevents it from conducting business as usual.

The team chose to attack the parasite's enzyme known as 14DM because it has a counterpart in fungi, which cause athlete's foot and ringworm, and such fungal infections are commonly treated with drugs that prevent 14DM from making ergosterol, a sterol required for membrane synthesis.

Writing  in Nature Medicine, scientists from the Fred Hutchinson Cancer Research Center and the University of Washington say they have demonstrated how to increase the number of  progenitor cells capable of rapid myeloid engraftment after cord blood transplantation. The discovery clears a major technical hurdle to making umbilical-cord-blood transplants more widely available for treating leukemia and other blood cancers.

Older people who suffer "mental lapses," or episodes when their thinking seems disorganized or illogical, may be more likely to develop Alzheimer's disease than people who do not have these lapses, according to a study published in the January 19, 2010, issue of Neurology.

These cognitive fluctuations, are common in a type of dementia called dementia with Lewy bodies, but researchers previously did not know how frequently they occurred in people with Alzheimer's disease and, equally important, what effect fluctuations might have on their thinking abilities or assessment scores.

People who experience trauma in childhood are more likely to pick up dangerous habits like smoking and contract lung cancer later in life as a result, say the authors of a new study in BMC Public Health. The researchers note, however, that the link is only partly explained by raised rates of cigarette smoking in victims of childhood trauma, suggesting that other factors may also be to blame.

Adverse event information was collected from 17,337 people between 1995 and 1997. Brown and his colleagues followed up on the medical records of these same people to study lung cancer rates in 2005.