Getting informed consent from desperate people and their families for experimental treatments is quite easy.

Researchers have succeeded in reconstructing the sea ice conditions in the Fram Strait for this critical period at the end of the last glacial and thus in finding a direct connection between changes in sea ice cover and fluctuations in the Gulf Stream.

A nine meter long sediment core served as a window into the past for the geologists. It was drilled on a Fram Strait expedition conducted on the research vessel Maria. S. Merian and has such clearly defined layers that the scientists can read it like a book. 

A new study has found that both type-1 diabetes and type-2 diabetes are the result of the same mechanism - the formation of toxic clumps of a hormone called amylin.

The results, based on 20 years' work in New Zealand, suggest that type-1 and type-2 diabetes could both be slowed down and potentially reversed by medicines that stop amylin forming these toxic clumps.

As well as producing insulin, cells in the pancreas also produce another hormone called amylin. Insulin and amylin normally work together to regulate the body's response to food intake. If they are no longer produced, then levels of sugar in the blood rise resulting in diabetes and causing damage to organs such as the heart, kidneys, eyes and nerves if blood sugar levels aren't properly controlled.

Even the most careful chosen meal can contain surprises and to defend against infectious microbial fifth columnists in the intestines, a dedicated contingent of immune cells keeps watch within the thin layer of tissue that divides the contents of the gut from the body itself. 

New research at Rockefeller University sheds light on the development of a unique class of immune cells known as intraepithelial lymphocytes (IELs) that reside in this critical interface. . 

Everyone's heard of the birds and the bees - why do they leave out the flowers that are being fertilized?

Maybe because it is too complicated. The fertilization process for flowering plants is particularly complex and requires extensive communication between the male and female reproductive cells. New research from an international team reports
in Nature Communications about discoveries in the chemical signaling process that guides flowering plant fertilization. 

Using a combination of genetic and optical techniques, researchers at the Champalimaud Neuroscience Programme have established the effect of serotonin on sensitivity to pain.

"Serotonin is a small molecule known to be implicated in a wide range of brain functions, from the control of sleep and appetite, to the regulation of complex emotional behaviours, This neurotransmitter is also popularly thought to contribute to feelings of well being and happiness, as some anti-depression medications work through increasing serotonin in the brain," says Zachary Mainen, CNP director and principal investigator of the Systems Neuroscience Lab.