On September 27, 2004, the front part of a baby mammoth’s body was found in Olchan mine in the Oimyakon Region of Yakutia. Specialists of the Museum of Mammoth of the Institute of Applied Ecology of the North, Academy of Sciences of Sakha Republic (Yakutia), have been thoroughly studying the finding and they have published the first results.

The remains were only the head, part of the proboscis, the neck area and part of the breast of the baby mammoth’s body. The body was mostly cut off behind the withers and shoulder area. The skin on the head was torn on the forehead and cinciput, the skull was damaged and the proboscis was torn off. The baby mammoth’s skin was well preserved - smooth, greyish-brown and even the tawny hair had fallen out and frozen into the ice near the body.

Tuberculosis kills two million people per year and so remains a very dangerous disease, though less so in America.

Researchers worldwide have been working to produce efficient tuberculosis vaccines but no one has created something that can ensure complete protection from the disease. The efficacy of one of the most widespread vaccines – BCG – varies from 80% to as little as 0%.

Specialists of the State Research Center for Virology and Biotechnology “Vector” have tested an experimental preparation for tuberculosis vaccinal prevention. The preparation is nontoxic and does not provoke an immune response in mice. Because it has not received all required verifications and approvals it cannot be called a vaccine yet.

Overexpressing a protein involved in the uptake of fat in muscle of mice can improve their tolerance to cold temperatures, researchers find in a new study that showcases the over-looked role muscle may play in the cold response.

When temperatures drop, mammals respond by generating heat (thermogenesis), through mechanisms like shivering and breaking down ‘brown fat’ (high energy fat cells that are especially prominent in newborns and hibernating animals).

Considering that muscle accounts for over one-third of body mass and muscle activity regulates fat metabolism, Dalan Jensen and colleagues found that increasing the muscle’s ability to use fat for energy had a profound impact on its contribution to thermogenesis.

A study of male attitudes to health and how they use health services challenges the usual stereotype that men are uninterested in their health. The results will surprise those people who envisage the Australian pub-going male as brusque and disinterested in all things medical.

Rather than procrastinating, men may delay going to the doctor so that they can watch a health problem to see if it will fix itself. Indeed, a picture emerges of men as personal health detectives, monitoring rather than ignoring symptoms, and visiting the doctor only if a problem fails to resolve itself.

Regeneration, the replacement of damaged or lost body parts, is a shared trait among some animal species – as any youngster who has cut an earthworm in half can attest to. But the repair of damaged tissue and organs in higher animals is also one of the primary goals of current stem cell research.

The common aquarium pet, zebrafish, is an excellent genetic model system, capable of regenerating its spinal cord, retina, heart and fins. A group of researchers writing in Genes & Development focused on fin regeneration, as it entails the coordination of a large number of different cells types to recreate the functional organ.

Their study reveals that microRNA depletion is a necessary step in tissue regeneration – a discovery with interesting implications for their use in regenerative medicine.

Bile acid derivatives can turn on the vitamin D receptor (VDR) without causing excess calcium buildup, researchers report, a finding that could lead to vitamin D therapies for conditions beyond just bone and skin disorders.

While calcium balance may be the most well-known role of vitamin D, this molecule –through VDR binding– regulates many functions including immunity and cell growth and thus has diverse therapeutic potential. However, while vitamin D-based drugs are effective against some cancers and microbial infections, the risk of excess blood calcium has limited their clinical use.