Scientists at North Carolina State University have discovered that the fungus-like pathogen that caused the 1840s Irish potato famine originally came from the Andes of South America.

By comparing the sequences of both the nuclear and the cellular powerhouse, mitochondria, of nearly 100 pathogen samples from South America, Central America, North America and Europe, Dr.

A meditation technique promoted by the controversial Maharishi
organization of Iowa claims significant decreases the severity of congestive heart failure in a small pilot study published in Ethnicity&Disease (Winter 2007).

The authors from the University of Pennsylvania evaluated 23 African American men and women, average age 64, who were recently hospitalized with New York Heart Association class II or III congestive heart failure. Participants were randomized to either the Transcendental Meditation (TM) technique or health education—in addition to usual medical care.

New research shows that a form of vitamin A used to treat acute promyelocytic leukemia induces changes in an unusual class of small molecules called microRNAs (miRNAs) in the leukemic cells.

The study also shows that three of these miRNAs inhibit the action of two genes important for cancer development, helping to explain how the drug works.

The drug is called all-trans-retinoic acid (ATRA) and it is considered the gold standard for treating the disease.

The study showed that ATRA raises the levels of three particular miRNAs in leukemia cells and that this rise coincides with a fall in activity of two important cancer-causing genes. The three are identified as miRNA-15b, miRNA-16-1 and let-7.

An international group of scientists has expanded the universal language for the genes of both disease-causing and beneficial microbes and their hosts. This expanded "lingua franca," called The Gene Ontology (GO), gives researchers a common set of terms to describe the interactions between a microbe and its host.

The Plant-Associated Microbe Gene Ontology (PAMGO) consortium and the GO consortium staff at the European Bioinformatics Institute approved and released more than 450 new terms for describing gene products involved in microbe-host interactions.

Oregon Health & Science University research shows how calcium regulates the recharging of high-frequency auditory nerve cells after they've fired a burst of signals, and it may have implications for neurological disorders.

The study by scientists at OHSU's Vollum Institute and the University of Arkansas for Medical Sciences, which appears in the current issue of the journal Nature Neuroscience, shows that calcium ions play a greater role in keeping in check the brain's most powerful circuits, such as those used for processing sound signals, than previously thought.

A penalty kick places a goalkeeper at such a disadvantage that only approximately 18% of penalty kicks are saved. However, some soccer fans think goalkeepers might save penalty kicks more easily by standing marginally to the left or right.

It turns out they're right! In an article published in the March issue of Psychological Science, Professors Rich Masters, John van der Kamp and Robin Jackson of the Institute of Human Performance at the University of Hong Kong found that penalty takers are more likely to direct the football to the side with more space.