Cancer cells are sick, but they keep growing because they don't react to internal signals urging them to die. Now researchers at Washington University School of Medicine in St. Louis have found an efficient way to get a messenger into cancer cells that forces them to respond to death signals. And they did it using one of the most sinister pathogens around — HIV.

"HIV knows how to insert itself into many different types of cells," says senior author William G. Hawkins, M.D., assistant professor of surgery and a member of the Siteman Cancer Center at the School of Medicine and Barnes-Jewish Hospital. "A portion of the HIV protein called TAT can transport biologically active compounds into cells. TAT is small, but it can move massive molecules.

Physicists at JILA have demonstrated that the warmer a surface is, the stronger its subtle ability to attract nearby atoms, a finding that could affect the design of devices that rely on small-scale interactions, such as atom chips, nanomachines, and microelectromechanical systems (MEMS).

Two biologists at Penn State have discovered a master regulator that controls metabolic responses to a deficiency of essential amino acids in the diet. They also discovered that this regulatory substance, an enzyme named GCN2 eIF2alpha kinase, has an unexpectedly profound impact on fat metabolism. "Some results of our experiments suggest interventions that might help treat obesity, prevent Type II diabetes and heart attacks, or ameliorate protein malnutrition," said Douglas Cavener, professor and head of the Department of Biology, who led the research along with Feifan Guo, a research assistant professor.

Physicists have for the first time stopped and extinguished a light pulse in one part of space and then revived it in a completely separate location. They accomplished this feat by completely converting the light pulse into matter that travels between the two locations and is subsequently changed back to light.

Matter, unlike light, can easily be manipulated, and the experiments provide a powerful means to control optical information.

A study at UCL (University College London) finds that a high-prevalence of male-killing bacteria active in many species of insect including the butterfly, actually increases female promiscuity and male fatigue.

The largest climate change in central North America since the age of the dinosaurs 65 million years ago, a temperature drop of nearly 15 degrees Fahrenheit, is documented within the fossilized teeth of horses and other plant-eating mammals, a new study reveals.

The overwhelming majority of previous climate-change studies on the 400,000-year transition from the Eocene to the Oligocene epochs, about 33.5 million years ago, focus on marine environments, but University of Florida vertebrate paleontologist Bruce MacFadden and his colleagues turned their attention to fossils from the Great Plains.