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Michael WhiteRSS Feed of this column.

Welcome to Adaptive Complexity, where I write about genomics, systems biology, evolution, and the connection between science and literature, government, and society.

I'm a biochemist

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Earlier this week I argued that biological systems posses dynamical properties that are biologically important, and understandable primarily through mathematical modeling. As an example, I discussed a paper that explored the advantages of double positive feedback loops in bistable switches.

I glossed over the math behind the model because of space and time constraints. (Constraints on a blog, you wonder? Well, I ran out of time, and once a blog post gets beyond 1000 words, the number people who read it to completion probably drops exponentially for every word over 1000.)
Yesterday evening, he succeeded in convincing his thesis committee to let him out with his PhD in hand. It's now Dr. Rugbyologist - if you thought he was belligerent before, just wait...


Hopefully he'll be back to blogging when the hangover wears off (and he finishes moving to his new position). Read the feed:

Why should we bother building mathematical models of biological systems? Scientists from other fields might wonder why one would as such a question - physicists, climate scientists, economists, engineers, and chemists all use mathematical models to understand the world.

Some biologists do too - individual proteins are studied with quantum mechanical models by biophysicists, enzyme reactions are modeled by biochemists, physiologists have mathematical models of the circulatory system, and population geneticists model the evolution of gene frequencies in populations.
Richard Fortey reviews The Genesis Enigma in The Times Literary Supplement:
Science is inextricably interwoven with cosmology, with theology, with epistemology, with ethics, politics, and psychology, all of them crucial to exploration into the human condition. A cosmology cannot be taken seriously that is not consistent with modern mechanics and astronomy, nor an epistemology that is naive in its understanding of operationalism, quantum uncertainty, or the Gödel theorems. To understand Zeno's paradoxes, we do not study the classics, but Weierstrass and Cantor.

- Herbert A. Simon, "Culture to the Nth Power", in Visions of Technology, ed. Richard Rhodes, p. 247






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