Ever since the logical positivists in the early 20th century, there has been a debate over whether science has made metaphysics obsolete. Is science all we need to describe and understand the ultimate meaning of reality? Even those who consider themselves philosophers of science can't agree on the answer to this question.
Metaphysics and its relation to science is the starting point for the discussion on this week's Philosopher's Zone Podcast. This is an excellent podcast that is enjoyable no matter what your level of knowledge is of philosophy. It is put out by the Australian version of public radio and the website includes full transcripts of each episode.