In new research appearing in the prestigious journal Nature Biotechnology, an international research team led by The Hebrew University of Jerusalem describes a new technique for growing human hepatocytes in the laboratory. This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations.

Research led by Dr. Keiji Tanimoto from the University of Tsukuba, Japan, has brought us closer to understanding the mechanisms underlying the phenomenon of genomic imprinting. In this intriguing event, one copy of a gene is 'turned off', or silenced, depending on whether it was derived from the mother or the father. The research team has identified a segment of DNA that is essential in the imprinting process for the closely linked Igf2/H19 genes, two of the first imprinted genes to be discovered. If these genes are incorrectly imprinted, it can lead to the overgrowth (Beckwith-Wiedemann) or dwarfism (Silver Russell) syndromes, and also has a role in some kidney and liver cancers.

Fast Radio Bursts - bursts of energy from space that appear as a short flashes of radio waves to telescopes on Earth - have baffled astronomers since first detected a decade ago.

Though only 16 have been recorded, there could be thousands of of these mysterious events each day.

(PHILADELPHIA) -- Researchers at Thomas Jefferson University have discovered why conventional efforts to block a tiny strand of ribonucleic acid, called microRNA, in triple negative breast cancer cells failed. In a study published December 2nd in the journal PLOS ONE, the new insight enables effective design of RNA blockers against previously intractable microRNAs.

(PHILADELPHIA) - Although a number of treatments exist to alleviate the symptoms of Parkinson's disease, to date, none reliably slow the progression of the disease. In 2013, a molecule called GM1 ganglioside showed promise in patients for not only relieving symptoms but also slowing disease progression. However, GM1 ganglioside has been difficult to make and to deliver to patients for regular use. Now, researchers at Thomas Jefferson University have demonstrated a way to help the brain of mice produce more of its own GM1 ganglioside in a study published December 2nd in the open access journal PLOS ONE.

When you see someone wandering all over the street because they are on the phone, it is irksome. When you have to reply to a text, not so much.

At Science 2.0 we call this phenomenon "mobile drift" but the American Academy of Orthopaedic Surgeons lumps such mobile deadwalkers under the term "distracted walking." They find that more than three quarters (78 percent) of U.S. adults believe that distracted walking is a "serious" issue; however, 74 percent of Americans say "other people" are usually or always walking while distracted, while only 29 percent say the same about themselves. 

Chemical triggers that make plants defend themselves against insects could replace pesticides, according to a new paper in Bioorganic&Medicinal Chemistry Letters which identifies five chemicals that trigger rice plants to fend off a common pest - the white-backed planthopper, Sogatella furcifera

The Ophel excavations at the foot of the southern wall of the Temple Mount have unearthed an impression of the royal seal of King Hezekiah, around 727-698 B.C. 

Measuring 9.7 X 8.6 mm, the oval impression was imprinted on a 3 mm thick soft bulla (piece of inscribed clay) measuring 13 X 12 mm. Around the impression is the depression left by the frame of the ring in which the seal was set.

The impression bears an inscription in ancient Hebrew script: "Belonging to Hezekiah [son of] Ahaz king of Judah," and a two-winged sun, with wings turned downward, flanked by two ankh symbols symbolizing life.

A study that included more than 20,000 women with stage IV breast cancer finds that survival has improved and is increasingly of prolonged duration, particularly for some women undergoing initial breast surgery, according to the report published online by JAMA Surgery.