The human papillomavirus (HPV) vaccine has been controversial in both the United States and European countries like Germany. It prevents about 70% of cervical cancers, cervical cancer is uncommon and highly treatable, and it will need another vaccine before girls who are given it even become adults. Along with those data issues, academic scientists and the public have been engaged in a culture war against pharmaceutical companies - that vaccines are exempt from ordinary lawsuits and that the vaccine was marketed heavily just after an expensive settlement by manufacturer Merck was not lost on the public.

No one knows you like you know yourself so if you think your memory is slipping, you may be onto something. Self-reported memory complaints are strong predictors of clinical memory impairment later in life. 

 Richard Kryscio, PhD, Chairman of the Department of of Biostatistics and Associate Director of the Alzheimer's Disease Center at the University of Kentucky, and colleagues asked 531 people with an average age of 73 and free of dementia if they had noticed any changes in their memory in the prior year. The participants were also given annual memory and thinking tests for an average of 10 years. After death, participants' brains were examined for evidence of Alzheimer's disease.

By Jonathan Borwein (Jon), University of Newcastle and Michael Rose, University of Newcastle

In our hyperactive media climate, where every incident is proof or not proof of something, it has become common to see claims that wildfires have become worse due to global warming even as American CO2 emissions have dropped.

Scientists have put a fire retardant on claims that Colorado's Front Range wildfires are becoming increasingly severe.

By Steve Ellen, Monash University

It’s Grand Final season – it might seem that nothing else matters about now.

Writing about the psychology of football is like writing about the psychology of love. A fool’s business. Nothing (so far) has quite made sense of how 100,000 people turn up to shout and scream, cry and gasp, and pin their fortunes on a bunch of athletes running around crashing into each other at the limits of human endurance.

It’s just good honest fun. Well, mostly honest.

Fan passion

The first animal model for ALS dementia, a form of ALS that also damages the brain, has been developed. This advance will allow researchers to directly see the brains of living mice, under anesthesia, at the microscopic level and will allow direct monitoring of test drugs to determine if they work. 

Stroke is one of the leading causes of death worldwide and while there are obvious environmental factors such as diet, exercise and behavior, many lines of evidence suggest that the risk of stroke is heritable. Yet until now, only a small number of genes associated with stroke have been identified. 

A new study in the Journal of Clinical Investigation identifies two genes that underlie cerebral small-vessel disease (CSVD), a risk factor for stroke.

Ordan Lehmann and colleagues at the University of Alberta analyzed genome-wide association data from individuals that received brain MRI scans as part of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) study.

In the developed world, people are having fewer children and living longer and that has led to a population that is older than in the past.

On average, life expectancy in developed countries has risen at a pace of three months per year, and fertility has fallen below replacement rate in the majority of Europe and some other developed countries. Most academic discussion of this trend has so far focused on potential problems - when social security was young there were over 20 workers per retiree and now there are 3 - and that is without the entire Baby Boom being retired and incurring healthcare costs.

Retinoblastoma is a childhood retinal tumor usually affecting children ages one to two and the most common malignant tumor of the eye in children. Left untreated, retinoblastoma can be fatal or result in blindness.

Retinoblastomas have been found to develop in response to the mutation of a single gene, the RB1 gene, demonstrating that some cells are only a step away from developing into a life-threatening malignancy.