A team of Cornell University scientists have discovered that a novel group of E. coli bacteria – containing genes similar to those described in uropathogenic and avian pathogenic E. coli and enteropathogenic bacteria such as salmonella, cholera, bubonic plague – is associated with intestinal inflammation in patients with Crohn’s disease.

Crohn’s disease, an incurable inflammatory disorder of the intestine – most commonly found in the lower part of the small intestine called the ileum – affects 1-in-1,000 people in Europe and North America. Thus far, gut bacteria have long been suspected in playing a pivotal role in the development of Crohn’s disease, but the specific bacterial characteristics that drive the inflammatory response have remained elusive.

‘Second generation’ biorefineries – those making biofuel from lignocellulosic feedstocks like straw, grasses and wood – have long been touted as the successor to today’s grain ethanol plants, but until now the technology has been considered too expensive to compete. However, recent increases in grain prices mean that production costs are now similar for grain ethanol and second generation biofuels, according to a paper published in the first edition of Biofuels, Bioproducts & Biorefining.

The switch to second generation biofuels will reduce competition with grain for food and feed, and allow the utilization of materials like straw which would otherwise go to waste.

University of Queensland researchers have identified microbial remains in some of the oldest preserved organic matter on Earth, confirmed to be 3.5 billion years-old.

The UQ team, led by School of Physical Sciences scientists Dr Miryam Glikson and Associate Professor Sue Golding as well as Associate Professor Lindsay Sly from the School of Molecular & Microbial Sciences, are the first to conclusively confirm the nature and source of the organic material.

“What we have found is the first visual confirmation of primitive microbial communities in what is considered to be the best preserved ancient organic matter on our planet,” Dr Glikson, the instigator of the research, said.

University of Cincinnati (UC) neurovascular researchers have identified a gene that—when suppressed or completely absent—may predispose a person to brain aneurysms.

Todd Abruzzo, MD, and his colleagues demonstrated that “knocking out” a gene known as endothelial nitric oxide synthase (NOS-3) in an animal model led to intracranial aneurysm formation in 33 percent of study subjects.

Scientists say this suggests that the gene may play an important role in the development of intracranial aneurysms.

Despite marketing claims, parents who want to give their infants a boost in learning language probably should limit the amount of time they expose their children to DVDs and videos such as “Baby Einstein” and “Brainy Baby.”

Rather than helping babies, the over-use of such productions actually may slow down infants eight to 16 months of age when it comes to acquiring vocabulary, according to a new study by researchers at the University of Washington and Seattle Children’s Hospital Research Institute.

The scientists found that for every hour per day spent watching baby DVDs and videos, infants understood an average of six to eight fewer words than infants who did not watch them.

Many of us experience a tinge of guilt as we delight in feelings of pleasure from our favorite indulgences, like splurging on an expensive handbag or having another drink.

Yet, in spite of documented ambivalence towards temptation and well-meaning vows not to succumb again, consumers often end up repeating the same or similar choices. A new study by Suresh Ramanathan (University of Chicago) and Patti Williams (Wharton School of Business, University of Pennsylvania) examines repeated impulsive behavior despite the presence of guilt – important research underscored by the increasing prevalence of binge drinking, obesity, and credit card debt.

As more people become fat, fat becomes more acceptable - even normal - and the definition of 'obesity' gets pushed further out.

Today, fat is the new 'normal', according to Florida State University Assistant Professor of Economics Frank Heiland and Federal Reserve Bank of Boston Economist Mary Burke, who are the co-authors of a paper published in the academic journal Economic Inquiry that argues that the ballooning weight of the population has fed even more collective weight gain as our perception of what is considered a normal body size has changed.

“This is a social force that we are trying to document because the rise in obesity has occurred so rapidly over the past 30 years,” said Heiland, who also is affiliated with FSU’s Center for Demography and Population Health.

People suffering from a severe retinal disease will sooner or later lose their eyesight considerably or even become completely blind.

Coordinated by the geneticist Ronald Roepman from Nijemegen, an international team has identified a further gene for the inherited retinal disease Leber Congenital Amaurosis (LCA) and discovered evidence how it functions. This represents new opportunities for gene therapy, a very promising approach for LCA since the disease is caused by a single mutation.

LCA causes blindness very early on – often shortly after or within a few months of birth. The disease can be caused through a single mutation in different genes; with the newly discovered LCA5 gene, ten disease-causing genes had been identified so far which are responsible for approx.

When it comes to generating neurons, researchers have found that not all embryonic stem (ES) cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each line. The discovery implies that culture conditions during ES cell generation -- which have yet to be identified -- can influence the developmental properties of human ES cells.

The report also describes a new technique for producing functioning neurons from stem cells that will be important for creating models of human neurodegenerative diseases.