Effector proteins are the bad guys that help bacterial pathogens do their job of infecting the host by crippling the body's immune system. In essence, they knock down the front door of resistance and disarm the cell's alarm system.

Now, researchers at the University of California, San Diego (UCSD) School of Medicine have identified a novel molecular target for an effector protein called YpkA, one of several effectors of the bacteria Yersinia – the pathogen responsible for the Middle Ages' "Black Death" and a virulent form of food poisoning today. Their study will be published online in the May 25 issue of Molecular Cell.

The frequency of intense hurricanes in the Atlantic Ocean appears to be closely connected to long-term trends in the El Niño/Southern Oscillation (ENSO) and the West African monsoon, according to new research from the Woods Hole Oceanographic Institution (WHOI). Geologists Jeff Donnelly and Jonathan Woodruff made that discovery while assembling the longest-ever record of hurricane strikes in the Atlantic basin.

A popular stereotype that boys are better at mathematics than girls undermines girls' math performance because it causes worrying that erodes the mental resources needed for problem solving, new research at the University of Chicago shows.

The scholars found that the worrying undermines women's working memory. Working memory is a short-term memory system involved in the control, regulation and active maintenance of limited information needed immediately to deal with problems at hand.

Integrating bio-chemical sensors into textiles for continuous monitoring of a person's health is the goal of the EU-funded BIOTEX ('Bio-sensing textile for health management') project.

As the first of its kind, the project is developing optimal electric, electrochemical and optical sensors which will be embedded into a textile substrate to create 'sensing patches' able to monitor the biochemical parameters of a user.

Scientists subjected mice to a diet that was 40 percent fat and lots of high fructose corn syrup - the human equivalent of a McDonald's meal and 8 cans of soda per day - and it took only four weeks for liver enzymes to increase and for glucose intolerance, the beginning of type II diabetes, to begin.

Heart researchers at the Center for Translational Medicine at Jefferson Medical College have used gene therapy to reverse heart failure in animals. In addition, they found that this gene therapy strategy had "unique and additive effects" to currently used, standard heart failure drugs called beta-blockers.