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The European Molecular Biology Laboratory [EMBL] has developed a new computational tool that makes images obtained with cutting-edge microscopes even sharper. The technological advance and its applications are published in this week's online issue of the journal Nature Methods.

Since the Single Plane Illumination Microscope [SPIM] was developed at EMBL in the early 2000s it turned into one of the most powerful tools in cell biology. SPIM allows scientists to study large, living specimen along many different angles, under real conditions and with minimal harm to the specimen.

Brain damage that was thought to be caused by hypoglycemic coma actually occurs when glucose is administered to treat the coma, according to a study in rodents led by researchers at the San Francisco VA Medical Center.

The results are surprising, say the authors, and may be of clinical significance for the treatment of diabetics in hypoglycemic coma, though they caution that the results cannot be immediately extrapolated to humans.

By analyzing the COSMOS field, the largest field of galaxies ever observed with the Hubble space telescope, an international team of scientists led by researchers from the California Institute of Technology (United States) and researchers from the associated laboratories of the CNRS and the CEA , made the first three-dimensional map of dark matter in the Universe using gravitational lensing effects. This historic first seems to confirm the standard theories on the formation of the large structures of the Universe. This study was presented in the January 7, 2007 issue of the journal "Nature."


Three-dimensional map of black matter in the COSMOS field. © ESA/NASA

The chemical bond between carbon and fluorine is one of the strongest in nature, and has been both a blessing and a curse in the complex history of fluorocarbons.


The changing Larsen-B Ice Shelf captured by Envisat on 22 February 2007 with its Advanced Synthetic Aperture Radar (ASAR). The Larsen Ice Shelf is a series of three shelves – A (the smallest), B and C (the largest) – that extend from north to south along the eastern side of the Antarctic Peninsula. Changes in ice shelves are believed to be indicators of climate change, as evidence suggests high latitudes experience the greatest atmospheric warming. Credits: ESA

A team of researchers from the UAB's Mutagenesis Group, led by Dr Jordi Surrallés, has identified one of the mechanisms used by cancer cells to resist chemotherapy.

In his paper, to be published in The EMBO Jorunal, Dr Surrallés describes how proteins of the Fanconi/BRCA pathway recognise the presence of genetic mutations in order to repair them. The researchers also found that alteration of this mechanism makes tumour cells much more sensitive to certain drugs. This discovery will make it possible to develop strategies to make tumours more vulnerable to chemotherapy.