Mathematicians and number buffs have their records. And today, an international team has broken a long-standing one in an impressive feat of calculation.

On March 6, computer clusters from three institutions – the EPFL, the University of Bonn and NTT in Japan -- reached the end of eleven months of strenuous calculation, churning out the prime factors of a well-known, hard-to-factor number that is a whopping 307 digits long.

Studies have shown that gastrointestinal (GI) tract function is often influenced by specific stimulants or reactors, which sometimes cause irritable bowel syndrome (IBS) or constipation. Two studies presented today at Digestive Disease Week® 2007 (DDW®) take a closer look at GI stimulation, including one examining the role of serotonin and reactions to certain types of foods and another looking at the potential therapeutic value of nerve stimulation for constipation. DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.

As many homeowners know, when stacking firewood, pieces should be placed close enough to permit passage of a mouse, but not of a cat chasing the mouse.

Now, imagine a woodpile where all those mouse passageways are packed with ice, the wood carefully removed, and you have an idea of what the latest photonic structure built by researchers at the University of Illinois looks like.

Peering into the body and visualizing its molecular secrets, once the stuff of science fiction, is one step closer to reality.

The research team is reporting that by looking at images from radiology scans - such as the CT scans a cancer patient routinely gets - radiologists can discern most of the genetic activity of a tumor. Such information could lead to diagnosing and treating patients individually, based on the unique characteristics of their disease.

Extremely drug resistant TB, or XDR-TB, is a serious problem in India, according to a study presented at the American Thoracic Society 2007 International Conference, on Monday, May 21.

The study, the first in India to look at the prevalence of XDR-TB, found this type of TB accounts for 8% of multi-drug-resistant cases, compared with about 4% in the United States.

In people with mild cognitive impairment, up to one drink of alcohol a day may slow their progression to dementia, according to a study published in the May 22, 2007, issue of Neurology®. Mild cognitive impairment is a transitional stage between normal aging and dementia that is used to classify people with mild memory or cognitive problems and no significant disability.

Researchers evaluated alcohol consumption and the incidence of mild cognitive impairment in 1,445 people. They then followed 121 people with mild cognitive impairment and their progression to dementia. The participants, age 65 to 84, were part of the Italian Longitudinal Study on Aging and were followed for three-and-a-half years.