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Study: Caloric Restriction In Humans And Aging

In mice, caloric restriction has been found to increase aging but obviously mice are not little...

Science Podcast Or Perish?

When we created the Science 2.0 movement, it quickly caught cultural fire. Blogging became the...

Type 2 Diabetes Medication Tirzepatide May Help Obese Type 1 Diabetics Also

Tirzepatide facilitates weight loss in obese people with type 2 diabetes and therefore improves...

Life May Be Found In Sea Spray Of Moons Orbiting Saturn Or Jupiter Next Year

Life may be detected in a single ice grain containing one bacterial cell or portions of a cell...

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There are many reasons why living in dense groups with others of your own kind is a good idea. Oftentimes, aggregations of a species serve as protection from predators and harsh environments or may be beneficial to future reproductive success. However, in the case of oyster larvae, the selection of a place to call home can be a life or death decision.

Increasing intake of antioxidant-rich cherries may help lower the risk of metabolic syndrome and cardiovascular disease, suggests a new study(1) presented today at the Experimental Biology annual meeting.

Researchers say the animal study is encouraging and will lead to further clinical studies in humans.

Triptolide is derived from a Chinese medicinal herb, named Lei Gong Teng, which has been used in traditional medicine to treat cancer, inflammation, and auto-immune diseases and, more recently, also has been tested in Phase I clinical trials as an anti-tumor agent.

Using a compound from Triptolide, Yale University researcher Dr. Craig Crews has been able to prevent the formation of kidney-destroying cysts in a mouse model of polycystic kidney disease. This ability holds out hope for what would be the first treatment, other than kidney transplant or frequent dialysis, for one of the most lethal of all kidney diseases worldwide.

By giving ordinary adult mice a drug - a synthetic designed to mimic fat - Salk Institute scientist Dr. Ronald M. Evans is now able to chemically switch on PPAR-d, the master regulator that controls the ability of cells to burn fat. Even when the mice are not active, turning on the chemical switch activates the same fat-burning process that occurs during exercise. The resulting shift in energy balance (calories in, calories burned) makes the mice resistant to weight gain on a high fat diet.

Northwestern University scientist Mary J.C. Hendrix and colleagues discovered that aggressive melanoma cells (but not normal skin cells nor less aggressive melanoma cells) contain specific proteins similar to those found in embryonic stem cells. This groundbreaking work led to the first molecular classification of malignant melanoma and may help to explain how, by becoming more like unspecialized stem cells, the aggressive melanoma cell gained enhanced abilities to migrate, invade and metastasize while virtually undetected by the immune system.

A new study from the University of Michigan Health System suggests that a compound in green tea may provide therapeutic benefits to people with rheumatoid arthritis.

The study looks at a potent anti-inflammatory compound derived from green tea. Researchers found that the compound -- called epigallocatechin-3-gallate (EGCG) -- inhibited the production of several molecules in the immune system that contribute to inflammation and joint damage in people with rheumatoid arthritis.