Our ability to learn, move, and sense our world comes from the neurons in our brain. The information moves through our brain between neurons that are linked together by tens of trillions of tiny structures called synapses.

Although tiny, synapses are not simple and must be precisely organized to function properly. Indeed, diseases like autism and Alzheimer's are increasingly linked to defects in the organization and number of these tiny structures. Now researchers at Thomas Jefferson University have found a new way in which synapses organization is controlled, which could eventually lead to better treatments for neurological diseases.

In nutrition, the saying goes, 'in the old days you had to be rich to be fat, now you have to be rich to be thin.' 

We have a biological mandate to try and ride out food booms and busts by consuming as many calories as we can, when we can. Rich people can take that out of their hands by paying for people to tell them to exercise and what not to eat and so they won't get gout like they once did. Poor people, with less disposable income, will shop for calorically-dense foods. 

Try to remember a phone number, and you're using what's called your sequential memory. This kind of memory, in which your mind processes a sequence of numbers, events, or ideas, underlies how people think, perceive, and interact as social beings. 

"In our life, all of our behaviors and our process of thinking is sequential in time," said Mikhail Rabinovich, a physicist and neurocognitive scientist at the University of California, San Diego.

The genome editing technique known as CRISPR-Cas9 ⁽¹⁾ has taken the biology world by storm. Initially it was primarily used to knock-out (literally, to make inoperative) specific genes, however, scientists have now figured out how to use the system to knock-in genes as well as edit the epigenome.

These features, along with the technique’s relative simplicity and ease of use, have led to CRISPR being adapted into a wide variety of fields such as bio-agriculture.

The Harlem Globetrotters had very little to worry about. After all, they had won 2,499 straight exhibition games against their foils, the Washington Generals. What could possibly go wrong? 

This one had all the suspense of a Harlem Globetrotters – Washington Generals game. (1)

Researchers have made a breakthrough in explaining how an incurable type of blood cancer develops from an often symptom-less prior blood disorder. All patients diagnosed with myeloma, a cancer of the blood-producing bone marrow, first develop a relatively benign condition called 'monoclonal gammopathy of undetermined significance' or 'MGUS'. 

MGUS is fairly common in the older population and only progresses to cancer in approximately one in 100 cases. However, currently there is no way of accurately predicting which patients with MGUS are likely to go on to get myeloma.

A new study projects that carbon sequestration in European cropland could store between 9 and 38 megatons of carbon dioxide (MtCO2) per year in the soil, or as much as 7% of the annual greenhouse gas emissions from agriculture in the European Union, at a price of carbon of 100 $/tCO2.

"However, if strict emission reduction targets are only adopted inside Europe, efforts within the EU to reduce emissions could lead to increased emissions in other parts of the world, which could significantly compromise emission reductions at global level" says IIASA researcher Stefan Frank, who led the study.

Scientists have developed a new test to identify patients who are at risk of suffering a relapse from testicular cancer.

Assessing just three features of a common kind of testicular cancer - called non-seminomatous germ cell tumor - can identify those at most at risk of relapse even where there is no evidence of tumor spread.

The researchers believe the test could be used in the clinic to make decisions about which patients should be given chemotherapy.

Scientists at The Institute of Cancer Research, London, analyzed 177 tumor samples from patients with stage I non-seminomatous tumors enrolled in clinical trials through the Medical Research Council (MRC) Clinical Trials Unit. 

Invasive aspergillosis (IA) is a serious disease of immune-compromised individuals and the most common invasive mold infection in humans. Although more than 250 different Aspergillus species are found in nature, and most contribute spores to the air we breathe, over 80% of human disease is caused by one particular culprit called Aspergillus fumigatus. A study published on October 15th in PLOS Pathogens explores what distinguishes this fungus from its relatives and likely makes it so dangerous.