An intense form of ultrasound that shakes a tumor until its cells start to leak can trigger an “alarm” that enlists immune defenses against the cancerous invasion, according to a study led by researchers at Duke University's Pratt School of Engineering.

The new findings from animal experiments suggest that once activated by the ultrasound, the immune system might even seek and destroy cancer cells, including those that have spread through the bloodstream to lurk in other parts of the body.

This high-intensity focused ultrasound, or HIFU, is in use or testing in China, Europe and the United States to kill tumors by heating them. But Duke researchers now find that HIFU might work even better if it is first delivered in a manner that just shakes the cells.

University of Cincinnati (UC) neurovascular researchers have identified a gene that—when suppressed or completely absent—may predispose a person to brain aneurysms.

Todd Abruzzo, MD, and his colleagues demonstrated that “knocking out” a gene known as endothelial nitric oxide synthase (NOS-3) in an animal model led to intracranial aneurysm formation in 33 percent of study subjects.

Scientists say this suggests that the gene may play an important role in the development of intracranial aneurysms.

While 10 years of bathing North Carolina pine tree stands with extra carbon dioxide did allow the trees to grow more tissue, only those pines receiving the most water and nutrients were able to store significant amounts of carbon that could offset the effects of global warming, scientists told a national meeting of the Ecological Society of America (ESA).

These results from the decade-long Free Air Carbon Enrichment (FACE) experiment in a Duke University forest suggest that proposals to bank extra CO2 from human activities in such trees may depend on the vagaries of the weather and large scale forest fertilization efforts, said Ram Oren, the FACE project director.

"If water availability decreases to plants at the same time that carbon dioxide increases, then we might not have a net g

Despite marketing claims, parents who want to give their infants a boost in learning language probably should limit the amount of time they expose their children to DVDs and videos such as “Baby Einstein” and “Brainy Baby.”

Rather than helping babies, the over-use of such productions actually may slow down infants eight to 16 months of age when it comes to acquiring vocabulary, according to a new study by researchers at the University of Washington and Seattle Children’s Hospital Research Institute.

The scientists found that for every hour per day spent watching baby DVDs and videos, infants understood an average of six to eight fewer words than infants who did not watch them.

Like navigating spacecraft through the solar system by means of gravity and small propulsive bursts, researchers can guide atoms, molecules and chemical reactions by utilizing the forces that bind nuclei and electrons into molecules (analogous to gravity) and by using light for propulsion. But, knowing the minimal amount of light required, and how that amount changes with the complexity of the molecule, has been a problem.

Now, by creating a quantum mechanical analog of Ulam’s conjecture, researchers at the University of Illinois and the University of California have expanded the flexibility and controllability of quantum mechanical systems.

Many of us experience a tinge of guilt as we delight in feelings of pleasure from our favorite indulgences, like splurging on an expensive handbag or having another drink.

Yet, in spite of documented ambivalence towards temptation and well-meaning vows not to succumb again, consumers often end up repeating the same or similar choices. A new study by Suresh Ramanathan (University of Chicago) and Patti Williams (Wharton School of Business, University of Pennsylvania) examines repeated impulsive behavior despite the presence of guilt – important research underscored by the increasing prevalence of binge drinking, obesity, and credit card debt.

Researchers from the Stem Cell Transplant Program and the Amyloid Treatment and Research Program at Boston University Medical Center (BUMC) have found that high-dose chemotherapy and blood stem cell transplantation can result in long-term survival for patients diagnosed with primary systemic light chain (AL) Amyloidosis.

BUMC was the first to begin using this treatment in 1994 and is the only center to publish these long-term outcome results.

AL amyloidosis occurs when plasma cells in bone marrow produce proteins that misfold and deposit in tissues, leading to organ failure and death. Between 1,200 and 3,200 new cases are reported each year in the United States, although researchers believe the disease is highly underdiagnosed.

As more people become fat, fat becomes more acceptable - even normal - and the definition of 'obesity' gets pushed further out.

Today, fat is the new 'normal', according to Florida State University Assistant Professor of Economics Frank Heiland and Federal Reserve Bank of Boston Economist Mary Burke, who are the co-authors of a paper published in the academic journal Economic Inquiry that argues that the ballooning weight of the population has fed even more collective weight gain as our perception of what is considered a normal body size has changed.

“This is a social force that we are trying to document because the rise in obesity has occurred so rapidly over the past 30 years,” said Heiland, who also is affiliated with FSU’s Center for Demography and Population Health.

Women see ‘masculine’ men as unsuitable long-term partners, new research suggests. Conversely, the psychologists from Durham and St Andrews Universities found that men with feminine facial features are seen as more committed and less likely to cheat on their partners.

The study, published in the current edition of Personality and Individual Differences, asked over 400 British men and women to judge digitally altered pictures of male faces made to look more masculine or feminine. The participants were asked to predict personality traits including sexual behaviour and parenting skills based on what they saw.

People suffering from a severe retinal disease will sooner or later lose their eyesight considerably or even become completely blind.

Coordinated by the geneticist Ronald Roepman from Nijemegen, an international team has identified a further gene for the inherited retinal disease Leber Congenital Amaurosis (LCA) and discovered evidence how it functions. This represents new opportunities for gene therapy, a very promising approach for LCA since the disease is caused by a single mutation.

LCA causes blindness very early on – often shortly after or within a few months of birth. The disease can be caused through a single mutation in different genes; with the newly discovered LCA5 gene, ten disease-causing genes had been identified so far which are responsible for approx.