Proteins, which form much of the molecular machinery required for life, are the targets of most drug molecules. One third of all proteins are membrane proteins – embedded within the cell’s fatty outer layer. While scientists can easily study the other two-thirds using such tools as antibodies, they have not had such methods to investigate the membrane-embedded portions of proteins.

To probe the secrets of these seemingly inaccessible proteins, researchers at the University of Pennsylvania School of Medicine have designed peptides that are able to bind to specific regions of transmembrane proteins, using computer algorithms, and information from existing protein sequence and structure databases.

By recognizing sugars, a technique developed by University of Michigan analytical chemist Kristina Hakansson sets the stage for new cancer diagnosis and treatment options.

A growing body of evidence points to assemblies of sugars called glycans attached to proteins on cancer cell surfaces as accomplices in the growth and spread of tumors. Researchers have been keen to characterize these glycans, but traditional analytical methods have not been sufficient.

From the Shangri-La Diet forums:

This is week 5 for me, and I have lost 7 pounds so far.

You may have read about the strange double asteroids dancing in space but putting together the pictures is a perfect example of science collaboration.

Prior to 2000, Antiope was just another asteroid. Then the 10-meter Keck II telescope in Hawaii discovered it was a doublet but not much else was known.

Two years ago, improved images from the European Southern Observatory's 8-meter Very Large Telescope (VLT) in Chile and Keck II determined an approximate orbit of the asteroids - but information was still sparse.

Enter crowdsourcing.

Attending the Tuesday lecture series of the ACS CINF division was a very educational experience, that provided me with some key insights into the present state of scientific collaboration. I observed that almost all people who presented were focused on different techniques that improved the way scientists could get information they need from sources that were not human, i.e., publications, databases, etc.

Recently week pictures were released by Taman Safari Indonesia Animal Hospital & Zoo of two Sumatran tiger cubs and a pair of orangutan babies who have been sharing a home over the last month. All four were orphaned, rescued and are now being housed together at the animal hospital.

Combining precise observations obtained by ESO's Very Large Telescope with those gathered by a network of smaller telescopes, astronomers have described in unprecedented detail the double asteroid Antiope, which is shown to be a pair of rubble-pile chunks of material, of about the same size, whirling around one another in a perpetual pas de deux. The two components are egg-shaped despite their very small sizes.

The asteroid (90) Antiope was discovered in 1866 by Robert Luther from Dusseldorf, Germany. The 90th asteroid ever discovered, its name comes from Greek mythology.

Scientists at MIT have created an ocean model so realistic that the virtual forests of diverse microscopic plants they "sowed" have grown in population patterns that precisely mimic their real-world counterparts.

This model of the ocean is the first to reflect the vast diversity of the invisible forests living in our oceans-tiny, single-celled green plants that dominate the ocean and produce half the oxygen we breathe on Earth. And it does so in a way that is consistent with the way real-world ecosystems evolve according to the principles of natural selection.

What would large women think if a dress sold for lower cost to women of smaller sizes?

Common sense says this would turn them off.

But swimmers react well to items claimed to improve speed if they know the product is given away free to Olympic swimmers.

If you perceive the person getting the good deal as being smarter than you, you are okay with it. You are even more likely to pay full price.