A new sequencing technique may provide a clearer picture of how genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's inherited risk for diabetes, heart disease and cancer, according to a study.
The powerful new tool may help researchers better explain why some people get sick and others do not despite being the same age and weight, or having the same bad habits (e.g. smoking). Researchers have long sought to determine these risks by looking at diet and variations in nuclear genes inherited from both parents. These analyses have left out differences in mitochondrial genes (mtDNA), the second kind of DNA in every cell, which we inherit from our mothers.