Glycoproteins are sugar-protein hybrid molecules that the protective mucus that lines our lungs and stomach and are also part of the fluid that lubricates our joints, the synovial fluid, and cover all our cells, with the sugar parts, the glycans, sticking out like a tiny forest of antennae.

 Researchers at ETH Zurich and Empa have also identified a surprising effect that glycans have on the water molecules that surround them.

In the fall of 2012, the European Medicines Agency approved the modified adeno-associated virus AAV-LPL S447X as the first ever gene therapy for clinical use in the Western world.

AAV-LPL S447X was developed for the treatment of a rare inherited metabolic disease called lipoprotein lipase deficiency which affects approximately 1-2 out of 1,000,000 people. Though incredibly rare, the disease causes severe, life-threatening inflammations of the pancreas. Afflicted individuals carry a defect in the gene coding for the lipoprotein lipase enzyme which is necessary for breakdown of fatty acids. AAV-LPLS447X shall be used as a viral vector to deliver an intact gene copy to affected cells.

For the past the 1,000,000 years the global climate has cycled every 100,000 years, between long glacial periods (with great masses of ice covering the continents in the northern hemisphere) and shorter interglacial periods, lasting around 10,000 years. It has been 12,000 years since the last one so enjoy that while it lasts.

However, within the long periods there have been abrupt climate changes, sometimes happening in the space of just a few decades, with variations of up to 10º C in the average temperature in the polar regions caused by changes in the Atlantic ocean circulation. These changes affected rainfall in southern Africa. 

Goals need to be flexible, according to a new paper.  People who set a goal of losing between 2 and 4 pounds will still lose an average of 3 lbs. while a person who targets 3 lbs. specifically has less chance of success. 

Consumers often have a choice about the types of goals they want to set for themselves, and they may want to repeat various goals over time. For example, consumers often reengage goals such as losing weight, saving money, or improving their exercise or sports performance.

Scholars have linked higher IQ at early school age to weight gain and increased head size in the first month of a baby's life.

The results were determined - as apparently intelligence is - by analyzing data from more than 13,800 children who were born full-term.  

The findings in Pediatrics were that babies who put on 40% of their birth weight in the first four weeks had an IQ 1.5 points higher by the time they were six years of age, compared with babies who only put on 15% of their birth weight. Those with the biggest growth in head circumference also had the highest IQs.

Fibromyalgia is a blanket term for a general painful condition that affects approximately 10 million people in the United States.

Because it lacks consistent symptoms and treatments, some doctors believe an unknown number of instances are psychosomatic but a new paper in PAIN MEDICINE concludes that fibromyalgia may have a rational biological basis, located in the skin.