Life has adapted to all sorts of extreme environments on Earth, among them, animals like the deer mouse, shimmying and shivering about, and having to squeeze enough energy from the cold, thin air to fuel their bodies and survive.
In a new paper, Scott, Cheviron et al., have examined the underlying muscle physiology from a group of highland and lowland deer mice. Peromyscus maniculatus - deer mice - were chosen because they exhibit the most extreme altitude range of any North American mammal, occurring below sea levels in Death Valley to more than 4,300 meters high in the mountains.