With war in Ukraine, Europeans are worried a key source of their food, Russia and Ukraine, is at risk.

They are right to be concerned. Food is a strategic resource but European countries chose to embrace higher cost lower yield alternatives to modern agriculture at home because they got cheap food from the east.

If an additional 290,000,000,000 loaves of bread were available, that would ease the strain worldwide. That is how much wheat is lost each year due to pests and diseases that the so-called organic process can't prevent. But science can.

The public are often baffled why environmental journalists attend climate conferences in person, using the rationalization that they do their jobs better if they can talk to people outside formal interviews.

What salesperson doesn't feel the same way? 

Science conferences are also well-attended, groups hosting them even note their high attendance, but the belief that any benefit from flying there and staying in a hotel is meaningful is usually held by people who enjoy going to conferences rather than empirical data. 

I make macaroni and cheese quite a lot. I like to eat it on Fridays and for friends and family on holidays. I have sampled mac and cheese all across the country. I am no Guy Fieri, but I have gotten around, and I can tell you with a great deal of confidence that most elite - which is to say costly - macaroni and cheese uses Velveeta. Or at least a key chemical in it.

The reason is not flavor. It is science. 

The Krebs cycle is named after Hans Krebs, who discovered it in 1937, part of the race to discover the central hub of cellular metabolism. In a cell’s mitochondria, it is a core part of the process by which cells “burn” sugars to make adenosine triphosphate (ATP), the cell’s energy-carrying molecule. 

Like the vast majority of readers of this column, I very strongly condemn the Russian invasion of Ukraine and the ensuing atrocities. War is never an answer to international controversies. And I would like to add: I am in favor of all sanctions that financially hit the aggressor, including cutting Russia from use of international banking circuits and similar impactful actions.

That said, I will say here what I think about this ongoing rush to find ways to hurt a country whose citizens are largely innocent of their leader's crimes. I think most of these creative initiatives are counter-productive, reaching the nonsensical, the irrational, and the plain nuts. 

A recent study describes a new species of vampyropod based on a 328-million-year-old fossil and pushes back the age of the group by nearly 82 million years. And shows that the oldest ancestors of the group of animals that includes octopuses and vampire squids had not eight but 10 arms. 

Vampyropods are soft-bodied cephalopods typically characterized by eight arms and an internalized chitinous shell or fin supports. Because they lack hard structures, Vampyropoda are not well represented in the fossil record. The new study is based on a vampyropod fossil from the collections of the Royal Ontario Museum. It was originally discovered in Montana and donated to the museum in 1988.

Over the course of the past two decades we have witnessed the rise of deep learning as a paradigm-changing technology. Deep learning allows algorithms to dramatically improve their performance on multivariate analysis tasks. Deep neural networks, in particular, are very flexible models capable of effective generalization of available data, with unbeatable results in their predictions. Indeed, from the outside, nowadays it looks as if the game changer in predictive analysis was the construction of large neural network architectures. But it was not.

COVID-19 vaccines have shown to be effective at preventing vaccines but the big win for public health is reduced effects if you get it anyway. If you don't have co-morbidities your relative risk is very low but if you do have them, every precaution is worth taking.

The vaccines come in many forms but two of note are the Janssen COVID-19 vaccine (Ad26.COV2.S) and Pfizer-BioNTech (BNT162b2), distinct because Janssen only requires one dose.  And the latter made "mRNA" part of the cultural lexicon. 

Which one led to fewer hospitalizations? They were both outstanding but there is a winner.

Being a woman is correlated to being twice as men to develop Alzheimer's disease, but lacking a scientific foundation for why, epidemiology is limited to noting it on a population level and moving on.

A new paper seeks to create a biological hypothesis. The authors say the C/EBPβ/AEP pathway is the core factor driving the pathogenesis of neurodegenerative diseases and searched for female hormones that are dramatically changed during menopause and tested which hormone selectively activates the C/EBPβ/AEP pathway. They have identified follicle-stimulating hormone (FSH) as the major pathogenic factor.