A study just published in JAMA Jan 5, reported that SSRI antidepressants are no better than placebo for most cases of depression. The authors reviewed 30 years of data and concluded that "the benefit of antidepressant medication compared with placebo may be minimal or nonexistent in patients with mild or moderate symptoms".

Scientists at the University of California San Francisco say a majority of published studies analyzing the relationship between Alzheimer's disease and smoking indicates that the habit is a significant risk factor for the disease. Researchers also found that studies funded by the tobacco industry tended to conclude that smoking protects against the development of AD, while independent studies showed that smoking increased the risk of developing the disease. The findings were published online today in the January issue of the Journal of Alzheimer's Disease.

Proapoptotic Peptides that target blood vessels in White adipose (fat) tissue and cause them to go undergo programmed cell death could become a model for future weight-loss therapies, says a study published online in Diabetes. The study found that obese animal models treated with proapoptotic peptides experienced decreased food intake and significant fat loss.

Fat tissue is vascularized, much like a tumor, and growth of fat tissue is highly dependent on the tissue's ability to build new blood vessels—a phenomenon called angiogenesis. Inhibiting adipose angiogenesis—essentially "starving" fat tissue—can reverse the effects of a high-fat diet in mice and rats.

The authors of a new study reported in the Journal of the American College of Cardiology say they know how much smoking affects cardiac health before and after a heart attack and have determined whether cutting back instead of completely kicking the habit will have a positive effect as well.

 Individuals who suffer memory loss may face a higher risk of stroke, regardless of whether they have been diagnosed with dementia, according to a new study published in Neurology.

For the study, 930 men in Sweden around the age of 70 without a history of stroke participated in three mental tests. The first test, called the Trail Making Test A, measures attention and visual-motor abilities. The second, the Trail Making Test B, measures the ability to execute and modify a plan. The third, the Mini Mental State Examination, is commonly used by doctors to measure cognitive decline.

 No vaccine currently exists for West Nile Virus, but a new therapeutic made from tobacco plants has been shown to arrest the infection, according to research conducted by Arizona State University scientists. The study, published this week in PNAS,  is the first to demonstrate a plant-derived treatment to successfully combat West Nile virus after exposure and infection.

"The goal of this research was twofold," said Arizona State University scientist Qiang Chen. "First, we wanted to show proof-of- concept, demonstrating that plant-made antibodies can work as effective post-exposure therapeutics. Secondly, we've sought to develop a therapeutic which can be made inexpensively so that the health care systems in developing countries can afford it."

A palm-sized device invented at Cornell that uses water surface tension as an adhesive bond just might make walking on walls possible for humans. The rapid adhesion mechanism could lead to such applications as shoes or gloves that stick and unstick to walls, or Post-it-like notes that can bear loads, researchers say.

The device is the result of inspiration drawn from a beetle native to Florida, which can adhere to a leaf with a force 100 times its own weight, yet also instantly unstick itself. Research behind the device is published in the Proceedings of the National Academy of Sciences.

Last Friday I was in Pisa, at the Scuola Normale Superiore (see picture), where italian members of the CMS Collaboration gathered for two days to discuss the status of their studies, exchange ideas, and try to coalesce common analysis efforts.