An analysis of about 1,300 peer-reviewed research articles found that few studies included men and women equally, less than one-third performed data analysis by sex, and there was wide variation in inclusion and matching of the sexes among the specialties and the journals reviewed, according to a paper JAMA Surgery.
Males and females can have different postoperative outcomes, complication rates, and readmission rates, so it is important to know if sex bias is pervasive in surgery. Adequately controlling for sex as a variable with inclusion, data reporting, and data analysis is important because data derived from clinical research are the foundation for evidence-based medicine.