Women and men appear to respond differently to the same biochemical manipulation. Major depressive disorder (MDD) is one of the most common mental disorders, and it is also one of the most studied. It is already known that reduced serotonin transmission contributes to the pathophysiology, or functional changes, associated with MDD and most of today’s most popular antidepressants block the serotonin “uptake site”, also known as the transporter, in the brain. It is also known that people with MDD are frequently found to have impaired impulse control.

Cancer-causing genes can work in more powerful and sneaky ways than have been realized. Scientists have shown that a gene named JAK that is closely related to a common cancer-causing gene in people tips the scales toward cancer in an unexpected manner. JAK disrupts the activity of an organism’s DNA on a broad scale, thwarting a critical molecular event very early on in an embryo’s development.

A team from the University of Rochester Medical Center made the finding through research involving fruit flies, which share much of the same complex cellular signaling as humans.

Peat and vegetation in northern areas may help protect permafrost from the effects of climate change, according to a recent study by McMaster researchers published in Geophysical Research Letters.

Found in arctic regions, permafrost is frozen soil that remains at or below 0 C for at least two consecutive years. Permafrost covers more than 30 per cent of the Earth's surface and about 42 per cent (four million sq. km) of Canada's land area.

"There is no doubt that northern regions are warming and permafrost is melting as shown by numerous observations and modeling studies," said Dr. Altaf Arain, co-author of the study and associate professor in the School of Geography & Earth Sciences.

Because Gary Taubes is probably the country’s best health journalist, his article in today’s NY Times Magazine (”Do We Really Know What Makes Us Healthy?”) about the perils of epidemiology especially interested me. It’s the best article on the subject I’ve read. He does a good job explaining what’s called the healthy-user bias — people who take Medicine X tend to make other healthy choices as well. Does wine reduce heart attacks? Well, probably — but people who drink more wine also eat more fruits and vegetables.

A groundbreaking environmental study to be published in a prestigious American science journal proves that mercury atmospheric emissions will end up in fish in as little as three years. Biologists from the University of Alberta in Edmonton, Canada, played a key role in designing and carrying out the experiment.

The study concludes that if mercury emissions from coal-fired power plants and other industrial activities were to be cut immediately, the amount showing up in fish would begin to go down within a decade.

This breakthrough study (called METAALICUS – Mercury Experiment to Assess Atmospheric Loading in Canada and the United States) involved government agencies and universities on both sides of the border. It has global implications.

Overturning the conventional theory that airborne soot emissions cause regional cooling it has been found that brown clouds of airborne soot can contribute up to a third of atmospheric warming anomalies in the tropics formerly ascribed to CO2 (50 percent of the atmospheric heating caused by CO2 emissions), with its effects ranging as far as the more-temperate American west coast and mountains ranges.

Increased solar radiance and decreased snowfall have been implicated as the true culprits in Kilimanjaro's glacier loss. The temperatures on Kilimanjaro's summits almost never rise above freezing, leading researchers to look for other causes for the ongoing glacial recession on Kilimanjaro's peak. Other studies have suggested that deforestation has severely impacted the arboreal microclimates that provide recharge precipitation to Kilimanjaro's glacial packs.

U.N. officials have stated that Kyoto's carbon-credit system is being subverted via cheating while contributing to the destruction of the ozone layer - counter-productive to the Montreal Protocol's goal to preserve it.

Quick: You’re walking by a store window and you see a sign that says, “20% off the original price plus an additional 25% off the already reduced sale price.” So, how much is the discount" Consumers often mistakenly think the total discount is 45% off the original price when, in fact, the true discount is 40%. A thought-provoking new study from the October issue of the Journal of Consumer Research explores why consumers frequently think a double discount is a better deal than a single discount of the same total magnitude.

“Retailers frequently use the strategy of double discounts for their regular promotions or to induce customers to open a credit card account with them. Such errors in peoples’ judgments of the net effect of multiple price discounts . . .