Would you want to know if you or your children had risk of hereditary cancer, a genetic risk for cardiovascular disease or carried the gene associated with developing Alzheimer's disease - even if they were risks that wouldn't be relevant for possibly decades or didn't have a cure?

 Researchers used data from a cross-sectional online survey of a nationally-representative sample of the U.S. population that was conducted as part of the C.S. Mott Children's Hospital National Poll on Children's Health and found that 80 percent showed the same interest in genome sequencing for themselves as they did for their kids and 59 percent wanted to know if they had disease risks.
 

Academics have written a lot of articles claiming their competitors in the private sector selectively publish trials that favor their own interests don't care as much about transparency as academia, but is that really true? 

When it comes to investigational drugs, devices and biologic therapies, the data is available and it shows that industry was actually 3X more likely to comply with legal requirements than academic studies after disclosure was mandated. 

Researchers at the Okinawa Institute of Science and Technology Graduate University's Brain Mechanisms for Behaviour Unit have found a surprise upon mapping the precise connectivity inside a brain structure called the neostriatum. The cell groups here do not seem to be talking to each other, and are less interdependent in their functioning than previously suspected. Their findings were published in Brain Structure and Function.

Once upon a time it was believed that greedy insurance companies were bad for patients - now they are a sign of the have's and have nots. A new analysis in Neurosurgery finds that brain tumor patients with private insurance have fewer medical complications and thus are in the hospital less than those who are on Medicaid or were uninsured between 2002 and 2011.

People have highly variable views on how much overdetection is acceptable in cancer screening, finds a UK survey in The BMJ this week. The authors say invitations for screening "should include clear information on the likelihood and consequences of overdetection to allow people to make an informed choice."

This article is part of a series on overdetection (overdiagnosis) looking at the risks and harms to patients of expanding definitions of disease and increasing use of new diagnostic technologies.

Findings published today in Scientific Reports looked at the pattern of variation of the South Asian monsoon over time and compared it with the evolution of African mole rats and bamboo rats as revealed by a full analysis of their relationships coupled with studies of their distribution in space and through time and of their evolutionary rates.

They found the first proof that weakening and strengthening monsoon rains played a key role in the evolution of these species. Over a period of 24 million years, the changes observed in the teeth and head shape of the rodents examined, matched the varying strength of the monsoon. Of the 38 species studied only six still exist today and the changing rains seem to have driven several species into extinction.