A stem cell capable of regenerating both bone and cartilage has been identified in bone marrow of mice. The discovery by researchers at Columbia University Medical Center (CUMC) is reported today in the online issue of the journal Cell.

The cells, called osteochondroreticular (OCR) stem cells, were discovered by tracking a protein expressed by the cells. Using this marker, the researchers found that OCR cells self-renew and generate key bone and cartilage cells, including osteoblasts and chondrocytes. Researchers also showed that OCR stem cells, when transplanted to a fracture site, contribute to bone repair.

Over 10 percent of patients using aspirin therapy for primary cardiovascular disease prevention shouldn't be doing so, according to a recent paper. 

They were likely either inappropriately prescribed it or do it over the counter, according to a new study that examined practice variations in aspirin therapy by accessing data from the National Cardiovascular Disease Registry Practice Innovation and Clinical Excellence (PINNACLE) Registry. The authors examined a nationwide sample of 68,808 patients receiving aspirin for primary cardiovascular disease prevention and evaluating aspirin guidelines by the American Heart Association, the U.S. Preventative Services Task Force, and other organizations.

Considering environmental effects such as a gravitational tidal force spread over a scale much larger than a galaxy cluster will be indispensable to explain the distribution and evolution of dark matter halos around galaxies, according to a comparison between theory and simulations by researchers at Kavli IPMU and collaborators.

Researchers at the Montreal Heart Institute announced today results showing that patients with cardiovascular disease and the appropriate genetic background benefit greatly from the new medication dalcetrapib, with a reduction of 39% in combined clinical outcomes including heart attacks, strokes, unstable angina, coronary revascularizations and cardiovascular deaths. These patients also benefit from a reduction in the amount of atherosclerosis (thickened walls) in their vessels. The detailed results are published in the prestigious Journal Circulation Cardiovascular Genetics. This discovery may also pave the way for a new era in cardiovascular medicine, with personalized or precision drugs.

Sex or no sex?  If you want to be healthier as a species over time, sexual reproduction is the way to go, according to a new study. 

It's a long-debated topic among biologists - some argue that sexual reproduction is superior because species don't accumulate harmful mutations as easily as in asexual reproduction.

Using various species of the evening primrose (Oenothera) as his model, Dr. Jesse Hollister, assistant professor at Stony Brook University in New York, and colleagues demonstrated strong support for reproducing sexually. "These findings allow us to understand why an enormous diversity of species around the world go through the laborious process of sexual reproduction," says Hollister.

Engineers in Austria have given us a blessing and a curse - they have created a giant laser system that sends beams in different directions, which makes them visible from many different angles. 

The angular resolution is so fine that the left eye is presented a different picture than the right one, creating a 3D effect.