Up to 50 percent of patients with heart failure have normal or near-normal ejection fraction, termed heart failure with preserved ejection fraction (HFPEF).

The risk of death in HFPEF may be as high as in heart failure with reduced ejection fraction (HFREF), but there is no proven therapy.

Beta-blockers improve outcomes in HFREF and may be beneficial in HFPEF, but data are sparse and inconclusive, and beta-blockers are currently not indicated for treating HFPEF, according to background information in the article.

Breathing secondhand marijuana smoke could damage your heart and blood vessels as much as secondhand cigarette smoke, according to preliminary research presented at the American Heart Association's Scientific Sessions 2014.

From 2000-2013 the global ocean surface temperature did not rise in spite of increasing greenhouse gas concentrations. This Global Warming Hiatus generated a lot of public and scientific interest and no small amount of skepticism about the accuracy of the numerical models created by climate scientists. But data is another matter entirely and as of April 2014 ocean warming has picked up speed again, according to a new analysis of ocean temperature datasets.  

When two
giant LIGO detectors
are switched on in the US next year, they will help scientists pick up the faint ripples of black hole collisions millions of years ago, known as gravitational waves. 

Black holes cannot be seen, but scientists hope the revamped detectors, which act like giant microphones, will find remnants of black hole collisions - and theoretical physicists hope experimentalists will give validation for their numerical model.

Home dialysis therapies may help prolong the lives of patients with kidney failure compared with hemodialysis treatments administered in medical centers, according to an upcoming study at ASN Kidney Week 2014 at the Pennsylvania Convention Center in Philadelphia, PA.

Home dialysis therapies are more convenient and less expensive than in-center treatment, but it's unclear whether all home therapies - which include peritoneal dialysis and home hemodialysis - can prolong patients' survival. Researchers led by Austin Stack, MD, MBBCh, FASN (Graduate Entry Medical School, University of Limerick, in Ireland) analyzed national data to compare dialysis survival among 585,911 patients who started dialysis in the United States between 2005 and 2010. 

Air pollution may play a role in the development of kidney disease, according to a study upcoming at ASN Kidney Week 2014 November 11-16 at the Pennsylvania Convention Center in Philadelphia, Pennsylvania.

There are wide variances in the prevalence of chronic kidney disease (CKD) across the United States, only part of which is explained by differences in individuals' risk factors. To see if air quality may also play a role, Jennifer Bragg-Gresham, PhD (University of Michigan) and her colleagues looked at 2010 Medicare information on 1.1 million persons as well as air-quality data for all US counties provide by the Environmental Protection Agency.