Identifying gene ancestry is crucial for computational genomics because genes passed down from a common ancestor tend to perform similar functions in the cell. Scientists exploit this similarity in tasks like predicting gene function, mapping human chromosomal regions to corresponding regions in model organisms, and reconstructing the regulatory circuitry that turns genes on and off.

Although computational biologists have developed methods to identify genes that share a common ancestor, current methods often lead to spurious conclusions when applied genes encode multi-domain proteins. Domains are sequence fragments that encode the basic building blocks of protein structure. Evolution makes new genes by mixing and matching domains in novel combinations, much like a child who builds a house, a car and a helicopter from the same LEGO kit by combining LEGO blocks in different ways.

This process, called domain shuffling, creates complex proteins that perform specific, critical tasks such as cell communication and binding to other cells. When one of these proteins fails, cancer is often the result. Domain shuffling allows rapid evolution of new proteins, but it also makes it close to impossible for scientists to determine their ancestry.

When atoms form molecules, they share their outer electrons and this creates a negatively charged cloud. The electrons buzz around between the two positively charged nuclei, making it impossible to tell which nucleus they belong to. They are delocalized.

Is this also true for the electrons located closer to the nucleus? And are those electrons spread out too, or do they belong to just one nucleus, i.e. are they localized?

These questions have been hotly debated for the last 50 years, and an international team of scientists says they have an answer - in true quantum theory fashion, they are both right.

MIT engineers have created ultrathin films made of polymers that could be applied to medical devices and other surfaces to control microbe accumulation. The inexpensive, easy-to-produce films could provide a valuable layer of protection for the health care industry by helping to reduce the spread of hospital-acquired infections, which take the lives of 100,000 people and cost the United States an estimated $4.5 billion annually.

The researchers found they could control the extent of bacterial adhesion to surfaces by manipulating the mechanical stiffness of polymer films called polyelectrolyte multilayers. Thus, the films could be designed to prevent accumulation of hazardous bacteria or promote growth of desirable bacteria.

“All other factors being equal, mechanical stiffness of material surfaces increases bacterial adhesion,” said Krystyn Van Vliet, the Thomas Lord Assistant Professor of Materials Science and Engineering.

High-salt diets may not increase the risk of death, contrary to long-held medical beliefs, according to investigators from the Albert Einstein College of Medicine of Yeshiva University.

They reached their conclusion after examining dietary intake among a nationally representative sample of adults in the U.S. The Einstein researchers actually observed a significantly increased risk of death from cardiovascular disease (CVD) associated with lower sodium diets.

The researchers analyzed data from the Third National Health and Nutrition Examination Survey (NHANES III), which was conducted by the federal government among a nationally representative sample of U.S. adults. These data were then compared against death records that had been collected by the government through the year 2000. The sample of approximately 8,700 represented American adults who were over 30 years of age at the time of the baseline survey (1988-1994) and were not on a special low-salt diet.

Ferdinand Magellan set out from Spain in 1519 with hopes of claiming the wealth of the Spice Islands, or Moluccas, for the Spanish. Two years later the explorer claimed the first European contact with a Pacific island culture when he landed on Guam – 1,500 miles north of the Spice Islands.

Was he the worst explorer ever? No, says North Carolina State University archaeologist Dr. Scott Fitzpatrick. Magellan’s historic circumnavigation of the globe was beset by unusual weather conditions, like El Niño, which eased his passage across the Pacific Ocean but sent him over a thousand miles off course.

Yes, El Niño, bane or boon to global warming debaters, depending on which side you are on. Screwing us all up then too.

Assistant Professor of Cognitive Science at Rensselaer Polytechnic Institute Mark Changizi says that actions like catching a football or easily moving through a room full of people requires something more than quickly responding to a situation — it requires our ability to foresee the future.

It takes our brain nearly one-tenth of a second to translate the light that hits our retina into a visual perception of the world around us. While a neural delay of that magnitude may seem minuscule, imagine trying to catch a ball or wade through a store full of people while always perceiving the very recent (one-tenth of a second prior) past. A ball passing within one meter of you and traveling at one meter per second in reality would be roughly six degrees displaced from where you perceive it, and even the slowest forward-moving person can travel at least ten centimeters in a tenth of a second.