The first national investigation of Medicare coverage of biologic disease-modifying drugs (DMARDs) found that in starting a single biologic DMARD, patients face more than $2,700 in co-payments each year before receiving relief from catastrophic coverage.

During the initial phase of coverage, most people are expected to pay a striking 29.6% of total biologic drugs costs (just under one-third) out-of-pocket, creating an enormous financial burden for patients with chronic, rheumatic diseases such as rheumatoid arthritis. 

Some studies find that the immune system, which protects our bodies from foreign invaders, plays a part in Alzheimer's disease, though the actual role of immunity in the disease is a mystery.

A new Duke University study in mice suggests that in Alzheimer's disease, certain immune cells that normally protect the brain begin to abnormally consume an important nutrient: arginine. Blocking this process with a small-molecule drug prevented the characteristic brain plaques and memory loss in a mouse model of the disease.

Human DNA accumulates damage over time and older bodies can't repair it as well as younger, leading to the obvious conclusion that damage builds up over time and leads to an irreversible dormant state known as senescence.

Cellular senescence is believed to be responsible for some of the telltale signs of aging, such as weakened bones, less resilient skin and slow-downs in organ function. DNA damage also seems to play a role in conditions called progerias, which cause premature aging. Progeria patients have mutations in genes responsible for DNA damage repair. Now researchers from the University of Pennsylvania have pinpointed a molecular link between DNA damage, cellular senescence and premature aging. 

A national survey suggests that slightly more than half of the older adults in the United States are now taking a daily dose of aspirin, even though its use is not recommended by the Food and Drug Administration for most people who have not yet had a heart attack or stroke.

The analysis observed that aspirin use is continuing to surge, especially among adults who are using it for "primary prevention," meaning in order to prevent an initial cardiovascular event, and in some cases to prevent cancer.

New research into how tendons age has found that the material between tendon fiber bundles stiffens as it gets older, which leads to older athletes being more susceptible to tendon injuries.

Researchers have found genetic overlap between Alzheimer's disease (AD) and two significant cardiovascular disease risk factors: high levels of inflammatory C-reactive protein (CRP) and plasma lipids or fats. The findings, based upon genome-wide association studies involving hundreds of thousands of individuals, suggest the two cardiovascular phenotypes play a role in AD risk - and perhaps offer a new avenue for potentially delaying disease progression. 

Faster increases in life expectancy do not necessarily produce faster population aging, a counterintuitive finding that came as a result of applying new measures of aging developed at the International Institute for Applied Systems Analysis (IIASA) in order to project future populations for Europe out to the year 2050.

Traditional measures of age simply categorize people as "old" at a specific age, usually 65, but previous research by Scherbov, Sanderson, and colleagues has shown that the traditional definition puts many people in the category of "old" who have characteristics of much younger people. 

In the developed world, we are aging rapidly. People age 85 and older make up the fastest growing age group in the United States and in other countries that trend will also increase.

Aging and aging well are not always the same thing, though, and issues like Alzheimer's are a concern. A new study of 256 people with an average age of 87 who were free of memory and thinking problems at the start of the study concluded that who participate in arts and craft activities and who socialize may delay the development in very old age of the thinking and memory problems that often lead to dementia.
Osteoporosis is a medical condition characterized by bones becoming brittle and fragile. Age-related loss in muscle mass and strength is considered analogous to osteoporosis but this “sarcopenia” is not recognized as a clinical condition even though it is linked to impaired physical function and contribute to disability, falls, and hospitalizations. Lower muscle mass and strength are also associated with lower bone mineral density and greater risk for osteoporotic fractures.

Why isn't sarcopenia more accepted? No valid diagnostic criteria whereas osteoporosis can be diagnosed based on widely accepted clinical standards.
Jonas the lemur defied his small size by living to the age of 29. David Haring, Duke Lemur Center

When Jonas the fat-tailed dwarf lemur died recently in captivity at the ripe age of 29 years, he was the oldest known of his species. But Jonas not only outlasted members of closely related lemur species held in captivity; he also lived much longer than science would predict based on his small size.