The artificial pancreas -- a device which monitors blood glucose in patients with type 1 diabetes and then automatically adjusts levels of insulin entering the body -- is likely to be available by 2018, conclude authors of a paper in Diabetologia (the journal of the European Association for the Study of Diabetes). Issues such as speed of action of the forms of insulin used, reliability, convenience and accuracy of glucose monitors plus cybersecurity to protect devices from hacking, are among the issues that are being addressed.

MADISON, Wis. -- Researchers at the University of Wisconsin-Madison have confirmed that a benign bacterium called Wolbachia pipientis can completely block transmission of Zika virus in Aedes aegypti, the mosquito species responsible for passing the virus to humans.

Matthew Aliota, a scientist at the UW-Madison School of Veterinary Medicine (SVM) and first author of the paper -- published today (July 1, 2016) in the journal Scientific Reports -- says the bacteria could present a "novel biological control mechanism," aiding efforts to stop the spread of Zika virus.

BOSTON (Embargoed until 2 PM EDT, June 29, 2016)--Butter consumption was only weakly associated with total mortality, not associated with cardiovascular disease, and slightly inversely associated (protective) with diabetes, according to a new epidemiological study which analyzed the association of butter consumption with chronic disease and all-cause mortality. This systematic review and meta-analysis, published in PLOS ONE, was led by Tufts scientists including Laura Pimpin, Ph.D., former postdoctoral fellow at the Friedman School of Nutrition Science and Policy at Tufts in Boston, and senior author Dariush Mozaffarian, M.D., Dr.P.H., dean of the School.

Messenger RNA (mRNA) is made up of exons and introns, that is, portions of genetic information that are "switched on" and "switched off", respectively. In order to reach maturation and be sent to the cellular "machine" that deals with protein synthesis, the non-coding fragments contained in the mRNA, the introns, need to be removed, whereas the coding sequences, the exons, have to be linked together. In humans, this "snipping and stitching" process, known as splicing, is governed by a huge machinery consisting of proteins and RNA, the spliceosome.

Women in the United States increasingly groom their pubic hair, especially those who are younger, white and have partners who prefer it, according to an article published online by JAMA Dermatology.

Previous research has suggested that most women report engaging in pubic hair grooming and pubic hair removal. Knowledge of grooming behaviors is important for health care professionals because these behaviors reflect cultural norms and can be a source of patient morbidity.

Tami S. Rowen, M.D., M.S., of the University of California, San Francisco, and coauthors surveyed women to examine demographic characteristics and motivations associated with pubic hair grooming habits. The study analysis included 3,316 women who answered a question on grooming.

ANN ARBOR--Free radicals cause cell damage and death, aging and disease, and scientists have sought new ways to repel them for years.

Now, a new University of Michigan study outlines the discovery of a protein that acts as a powerful protectant against free radicals. Ironically, the protein is activated by excessive free radicals. Human mutations of the gene for this protein are previously known to cause a rare, neurodegenerative disease.

Lysosomes, which comprise the cell's recycling center, are crucial for cleaning up injured and dying parts of the cells, said lead researcher Haoxing Xu, U-M associate professor of molecular, cellular and developmental biology.

Nerves in the central nervous system of adult mammals do not usually regenerate when injured. The granule cell, a nerve cell located in the cerebellum, is different. When its fibres, called parallel fibres, are cut, rapid regeneration ensues and junctions with other neurons called "synapses" are rebuilt. The precise mechanism for this was unclear.

Researchers at Hokkaido University in Japan, together with colleagues from Sapporo Medical University School of Medicine and Niigata University, investigated the effect of a specific glutamate receptor, called GluD2, on parallel fibre regeneration.

Medical devices approved first in the European Union (EU) are associated with a greater rate of safety issues, finds a study published by The BMJ today.

Clinical trial results for many new medical devices that could guide treatment decisions also remain unpublished or unavailable up to five years after approval, the findings show.

As such, the researchers call for greater regulatory transparency to enable patients and clinicians to make informed decisions about treatment.

Medical devices play an important role in patient care, but their approval and regulation are handled differently in the EU and US.