In a genome-wide analysis of 13 metastatic prostate cancers done on men who died of metastatic prostate cancer and whose tissue samples were collected after a rapid autopsy, scientists found consistent epigenetic signatures across all metastatic tumors in each patient.
The discovery of stable epigenetic marks that sit on the nuclear DNA of cancer cells and alter gene expression, defies a prevailing belief that the marks vary so much within each individual's widespread cancers that they have little or no value as targets for therapy or as biomarkers for treatment response and predicting disease severity.
So Coca-Cola and Pepsi Cola both introduced new ad campaigns. Pepsi went the traditional route (i.e. boring) once again and signed another fit superstar to sing about how awesome their soda is.
Thanks, Beyoncé, it's all been done, but I am thrilled you got $50 million to endorse it.
Credit and link: GQ Magazine
Coke did something really weird, for being supposedly an evil, mercenary, Big Corporation bent on exploiting children at all costs - they addressed the claims about soda and obesity in their ads.
A new image from the Atacama Pathfinder Experiment (APEX) telescope in Chile shows a beautiful view of clouds of cosmic dust
nebula NGC 1999
in the region of Orion. While these dense interstellar clouds seem dark and obscured to visible-light observations, APEX’s LABOCA camera can detect the heat glow of the dust and reveal the hiding places where new stars are being formed. But one of these dark clouds is not what it seems.
VTT Technical Research Centre of Finland has developed an automatic ice detection system for cars that makes use of a new, real-time method of obtaining information on a road's actual slipperiness.
Obviously, such a system helps drivers avoid personal injuries and damage to vehicles in slippery road conditions. Not only are vehicles are warned in advance of a road's actual slipperiness, if the road becomes slippery, other vehicles arriving in the area will also be warned immediately.
Predicting weather events is more mysticism than science and it's only after the fact that predictions are recalibrated to try and hone in on more accuracy. Hurricane Sandy in the eastern United States was predicted to be a super-storm but by the time it hit New York City was a regular old tropical storm, though one that became a welcome $17 billion federal stimulus plan and a call for action on global warming that did not cause it.
During our zeal to recapture manufacturing like Apple iPhone and solar panel construction during the last four years, something obvious was ignored; the environmental hazards were never going to be acceptable in the USA. The rich people who can afford the latest technology turn a blind eye to non-union wages, slave labor and environmental impact as long as it is happening in th developing world.
Optimal Monitoring has produced a free eBook about the Department of Energy and Climate Change consultation period, which is open until the end of January.
The Department of Energy and Climate Change (DECC) has invited companies to influence the latest Climate Change Bill and UK government energy policy. This consultation period on the UK draft Energy Bill is open until January 31st, 2013 and asks for ideas on how the Government can help businesses reduce their energy usage and therefore their cost. Carbon monitoring software provider Optimal Monitoring has created a free guide which addresses the opportunities the DECC consultation period presents for businesses and landlords to influence the Energy Bill.
A century ago, “past” and “future”, previously strictly apart, mixed up and merged.Temporal terminology improved.Today, not actualized quantum states, that is merely “possible” alternatives, objectively “exist” (are real) when they interfere.Again, two previously strictly immiscible realms mix.
Two weeks ago I got a call inviting me to attend one of the inauguration balls for President Obama. But it wasn't to be held in Washington, D.C. it was in Texas.
Texas? you might think, but aren't Democrats irrelevant in Texas, almost as irrelevant as Republicans are in California?
Psychiatrist Dr. Eric Hollander says the hygiene hypothesis - the idea that by eliminating some harmful organisms we are weakening our immune systems - may be a reason to study the use of ingesting the eggs of parasitic worms to treat autism.
He gets to jump on a few hot button cultural topics that way, autism and a medical idea that has caught on with the usual anti-science hippies and the more normal crowd who got sold the idea that anti-bacterial soaps were necessary if they care about kids.
The kicker is that the psychiatrist got the idea when he noticed one of his patients’ behavior improve while self-medicating with Trichuris suis ova (TSO), the eggs of a whipworm. That passes for a journal paper in the social sciences.
I am changing my nickname on a few sites I visit - ones where a nickname is useful - to "allhadronic". The name makes reference to the hadronic final state of certain particle decays. Hadron comes from ancient greek and means "strong", and indeed the strong force is the one responsible for the binding of quarks and gluons inside protons, neutrons, and other unstable particles, collectively also called hadrons.
"Believe it or not—and I suspect most readers will not—there's a liberal war on science. Say what?"
So begins famed skeptic Michael Shermer's review of "Science Left Behind" in his Scientific American column this month. Now, in the book, I make it pretty clear that liberals are not the problem, progressives are, but a baffling number of people on the left seek to use the terms interchangeably. Why, I don't know, there was never a need for two words if they are the same thing, but it explains why at San Francisco protests you can see people claiming to be Trotsky-ites palling around with people claiming to be Lenin-ites with people claiming to be Mao-ists selling Che Guevara t-shirts; they don't know what words mean.
Almost three years have passed since the US
patent for a Domestic
Animal Telephone was issued. The patent describes :
“A phone for pets and pet owners is
taught [sic?] which allows the owner to call the house and
‘talk’ to the pet”.
But then, in Feb. 2011 a
new patent was issued (also entitled 'Domestic Animal Telephone') to the same inventors – at first
glance strikingly similar to the original :
It has been a while since the last time I posted the last riddle of this series. It was fun though, so upon seeing the graph below I immediately decided I would use it here, to let you guess what it is about. Please use the comments thread to provide your input: what does the graph represent ? What are the different coloured lines ? Why the funny behaviour ? What is on the x axis ? And on the y axis ?
Of course it is virtually impossible to answer all the above without being given some hint. I can tell you it has to do with LHC searches, and that is all the help I am going to give you!
Studies are revealing new details about a molecular surveillance system that helps detect and correct errors in cell division that can lead to cell death or human diseases.
The purpose of cell division is to evenly distribute the genome between two daughter cells. To achieve this, every chromosome must properly interact with a football-shaped structure called the spindle. However, interaction errors between the chromosomes and spindle during division are amazingly common, occurring in 86 to 90 percent of chromosomes, says cell biologist Thomas Maresca at the University of Massachusetts Amherst. The key to flawless cell division is to correct dangerous interactions before the cell splits in two.
“It is demonstrable,” said he, “that things cannot be otherwise than as they are; for as all things have been created for some end, they must necessarily be created for the best end. Observe, for instance, the nose is formed for spectacles, therefore we wear spectacles. The legs are visibly designed for stockings, accordingly we wear stockings.”
- Candide by Voltaire
Humans are unique among the great apes (of which we are one) in various ways. One of them is our possession of a very long Achilles tendon, which is quite short in chimpanzees, gorillas, and orangutans.
Safe, Tasty, Nutritious Almonds We Shouldn't Take For Granted
Sometimes we need to hear about things that are working well in our food system. I'd like to describe a case where sound regulation and well-applied technology combine to protect us from a significant risk posed by a natural chemical called Aflatoxin - one of the most toxic and carcinogenic chemicals known.
San Francisco 49ers quarterback Colin Kaepernick is going to take the field in two hours and it won't just be a vindication of the decision by coach Jim Harbaugh to replace Alex Smith and his 13-3 run with a passer rating over 100 - Harbaugh can't lose in the eyes of the public even if the team does - it will be a vindication of science.
Public health scholars in Spain say they have done the first comparative study on the evolution of sperm quality in young Spanish men and found that over a ten year period, spermatozoid concentration in men between 18 and 23 years in the regions of Murcia and Almeria has dropped by an annual average of 2%.
The multidisciplinary study headed by the Department of Preventative Medicine and Public Health of the University of Murcia (UMU) found that "total sperm count and concentration has declined amongst young men in the south-east of Spain in the last decade." More specifically, the decrease amounts to 38%.