Neuroscientists from the University of Southampton investigating alcohol dependency and withdrawal in C. elegans worms say they exhibit alcohol-dependent behaviors similar to humans, despite their evolutionary distance, and very simple brain consisting of just 302 nerve cells.
The research, published in PLoS One, shows that withdrawal symptoms could be relieved by small doses of alcohol. However, easing the effects can increase dependency.
In humans, the symptoms are manifested in anxiety, agitation and, in extreme cases, seizures. The worms, as video footage shows, also became overactive in alcohol withdrawal and showed spontaneous and deep body bends – a behavior rarely seen in 'teetotal' worms.