Phase 2 data showing a reduction in amyloid-beta plaques in early Alzheimer's patients is good enough for FDA to give it temporary approval under their Accelerated Approval pathway.

The positive results occurred in mild cognitive impairment or mild dementia patients. Lecanemab-irmb is a 100 mg/mL injection for intravenous use, a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble (“protofibril”) and insoluble forms of amyloid beta (Aβ) for the treatment of Alzheimer’s disease (AD). The approval is based on Phase 2 data that demonstrated that LEQEMBI reduced the accumulation of Aβ plaque in the brain, a defining feature of Alzheimer's Disease.

Going to an area where there are a lot of wind vanes can be shocking. The noise and environmental blight for so little energy isn't worthwhile, and needing to get exemptions from endangered species laws due to deaths of avians like eagles make them a real negative.

Solar panels have a little better cultural response but can still be unattractive. If you are a wealthy elite who doesn't like the appearance, or a government building using taxpayer funds, you may be able to turn architectural constraints into alternative energy without ruining the aesthetic. The archaeological park of Pompeii and the Portuguese city of Evora are creating solar panels that look like ancient Roman tiles or terracotta bricks to match the skyline.

Inscriptions on the walls and crosses in a grotto first found by grave robbers in Lachish national park of the Judean lowlands west of Jerusalem have led archaeologists to conclude it was dedicated to Salome, associated with the birth of Jesus Christ in early Christian accounts.  The Jewish burial chamber and ossuaries dating back to the Roman period became part of a Christian chapel during the Byzantine era until the region was captured by the Rashidun Caliphate in the middle of the 7th century.

From insulin to lowering environmental strain to grow food, genetic engineering is one of the marvels of the 20th century. In the 21st, CRISPR-Cas9 or something else may achieve the same lofty status but genetic engineering isn't done yet.

Giant blue and humpback whales migrate across the ocean to breed and give birth in waters where predators are scarce.

A new analysis of the fossil bed in the Berlin-Ichthyosaur State Park (BISP) in Nevada’s Humboldt-Toiyabe National Forest suggests that nearly 200 million years before giant whales evolved, school bus-sized marine reptiles called ichthyosaurs may have been making similar migrations to breed and give birth together in relative safety.

Nevada is east of the very large state of California, and the study offers a possible explanation why at least 37 of these marine reptiles came to meet their ends in the same locale.

The Donnan electric potential arises from an imbalance of charges at the interface of a charged membrane and a liquid but detecting it directly has not been possible. Until now.