There's a little bit of MacGyver in all of us so even if it's unlikely to come up in our day-to-day lives, it would be nice to know how to do an artificial heart transplant in case it becomes really, really necessary, like you need to save a third world dictator or his second-in-command will launch a nuclear bomb.
The Journal of Visual Experiments is here to help. They have made it possible to watch the implantation of the SynCardia temporary Total Artificial Heart as you read their journal article. The paper and video both describe the case of a 60-year-old male with hypertrophic cardiomyopathy. Both detail the implantation surgery. They also discuss perioperative complications, postoperative care and selection of good candidates for the procedure.
Originally used as a permanent replacement heart, the SynCardia Total Artificial Heart is currently approved as a bridge to transplant for people suffering from end-stage biventricular heart failure in which both ventricles can no longer pump enough blood for a person to survive.
Pretreating the arterial outflow grafts. The aortic and pulmonary artery grafts are presealed with Coseal Surgical Sealant, a synthetic hydrogel used as an adjunctive sealant for vascular grafts. Previously the grafts were preclotted with patient's own blood prior to heparinization. Credit: DOI: doi:10.3791/50377
"Patients often present with cardiogenic shock and multi-system organ dysfunction," according to the paper by Drs. Daniel G. Tang, Keyur B. Shah, Michael L. Hess and Vigneshwar B. Kasirajan. "Excision of both ventricles and orthotopic replacement with the [SynCardia Total Artificial Heart] is an effective…therapy for rapid restoration of blood flow and resuscitation."
Heart failure patients who are extremely sick can get a second chance at life with the SynCardia Total Artificial Heart. It is the only approved device that eliminates the source of end-stage biventricular (both sides) heart failure in which the native heart ventricles can no longer pump enough blood for the patient to survive.
"The main advantage of the Total Artificial Heart over left ventricle assist devices [LVADs] is the [SynCardia Total Artificial Heart] allows for high-flow biventricular support," Tang, VCU assistant professor of cardiothoracic surgery, says in the video, "as well as the ability to treat a wide range of complex cardiac pathology that may not be ideally treated with isolated [LVAD] support."
Citation: Tang, D. G., Shah, K. B., Hess, M. L., Kasirajan, V. Implantation of the Syncardia Total Artificial Heart. J. Vis. Exp. (89), e50377, doi:10.3791/50377 (2014).
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Part I: Bee Deaths Mystery Solved? Neonicotinoids (Neonics) May Actually Help Bee Health
- Part II: Bee Deaths And CCD - Flawed Chensheng Lu Harvard Studies Endanger Bees
- Bitcoin And Anonymity: User's Identity Can Be Revealed Much Easier Than Thought
- Is The Micropower Revolution Here?
- Not Neonics: Parasites Are Bad For Honey Bees
- Chronic Pain Isn't All In The Brain
- On integrating out short-distance physics
- "I have always thought that that formulas like (1) are not clear . If G(u) is a primitive of f(u)..."
- "I am indeed checking with vanEnglesdorp even though the matter seems quite clear cut to me: showing..."
- "Hi, the comics linked below seems to deal with a similar stuff. http://www.smbc-comics.com/?id=3554#comi..."
- "they don't see how it damages the economic system that made America great in the past. Huh? Empirical..."
- "Hank, any experiment/study can test any thesis. If Lu's goal was to test field realistic doses..."
- Two studies identify a detectable, pre-cancerous state in the blood
- Nervous system may play bigger role in infections than previously known
- NIAID/GSK experimental Ebola vaccine appears safe, prompts immune response
- Heat-conducting plastic developed at U-Michigan
- Trial shows new imaging system may cut X-ray exposure for liver cancer patients