In diseases such as asthma and chronic obstructive pulmonary disease (COPD), the body produces too much mucus, making breathing difficult. New research from Washington University School of Medicine in St. Louis provides clues to potentially counteract inappropriate mucus production.

"The new study lays the groundwork for developing treatments for diseases such as asthma, COPD, cystic fibrosis and even certain cancers," said senior author Thomas J. Brett, PhD, assistant professor of medicine. "It also solves a 20-year mystery about the role of a protein that has long been associated with these diseases."

How does a mother transition genetic control to offspring early in development?

It's part of a larger mystery regarding how embryos regulate cell division and differentiation into new types of cells.

A new article in Cell provides some insight into the mechanism for this genetic hand-off, which happens within hours of fertilization, when the newly fertilized egg is a zygote.

A new paper notes that the Campanian Ignimbrite eruption in Italy 40,000 years ago, one of the largest volcanic cataclysms in Europe and responsible for injecting a significant amount of sulfur-dioxide (SO2) into the stratosphere, coincided with the final decline of Neanderthals as well as with dramatic territorial and cultural advances among modern humans.  

Scientists have long debated if this eruption and the resulting volcanic sulfur cooling and acid deposition could have contributed to the final extinction of the Neanderthals more than climate change or hominin competition. 

A new paper tests this hypothesis using a climate model. 

The leading theory of what causes ice ages around the world -- changes in the way the Earth orbits the sun- has been cast into doubt by a new study.

The study raises questions about the Milankovitch theory of climate, which says the expansion and contraction of Northern Hemisphere continental ice sheets are influenced by cyclic fluctuations in solar radiation intensity due to wobbles in the Earth's orbit; those orbital fluctuations should have an opposite effect on Southern Hemisphere glaciers.

A new study finds that even a brief nap can significantly improve memory retention of learned material.

Saarland University graduate student Sara Studte, PhD supervisor Axel Mecklinger and co-researcher Emma Bridger have examined how power naps influence memory performance.

A comprehensive study examining clinical trials of more than 95,000 patients has found that glucose or sugar-lowering medications prescribed to patients with diabetes may pose an increased risk for the development of heart failure in these patients.