Enrollment in a randomized Phase II clinical trial of Pracinostat in combination with azacitidine in patients with previously untreated intermediate-2 or high-risk myelodysplastic syndrome (MDS) has been completed. The multi-center, placebo-controlled, double-blind study enrolled a total of 108 patients with a one-to-one randomization.

The Company plans to unblind the study approximately six months after the last patient was enrolled and report topline data in Q1 2015.

Solar cells are the future but for now they are resource-intensive, expensive and not very efficient - but the researchers in a new study can help with those first two. To make a solar cell, machines etch nanoscale spikes into a silicon wafer in order to maximize its surface area and the amount of sunlight that can reach it.

Metal particles have been used as a catalyst in this process because etching is accelerated near metal particles. At first, gold was the metal of choice but that was never going to work in mass production so scientists found a way to switch to silver particles - much cheaper at around $20 per troy ounce but still not cost-effective enough for mass use, even in small amounts, when it comes to even a small, but typical for solar, 100MW facility.

Donald Spector is Chairman of New York College and just received Patent# 8,823,512 for a Wearable Biosensor, which he is donating to the college. The Wearable Biosensor patent predates the patents of the industry's leading technology companies, making it extremely valuable to a college, which can license it off to an Intellectual Property company that will get rich suing everyone. Why can he afford to do that?

Because he has a lot more patents. He is the most prolific living inventor that most people could never identify by name.

A mutation  in a gene called KNSTRN, which is involved in helping cells divide their DNA equally during cell division, is caused by ultraviolet light is likely the driving force behind millions of human skin cancers, according to new research.

Genes that cause cancer when mutated are known as oncogenes. Although KNSTRN hasn't been previously implicated as a cause of human cancers, the research suggests it may be one of the most commonly mutated oncogenes in the world.

A newly developed antifungal named isavuconazole is as effective as voriconazole against invasive mold disease in cancer patients with less adverse effects, according to phase 3 clinical data.

With age, our cells gradually lose their capacity to repair damage, even from normal wear and tear. A new paper discusses why this decline occurs in our skeletal muscle. 

A team led by Dr. Michael Rudnicki, senior scientist at the Ottawa Hospital Research Institute and professor of medicine at the University of Ottawa, found that as muscle stem cells age, their reduced function is a result of a progressive increase in the activation of a specific signaling pathway. Such pathways transmit information to a cell from the surrounding tissue. The particular culprit identified by Dr. Rudnicki and his team is called the JAK/STAT signalling pathway.