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Researchers at the University of Missouri-Columbia recently created a model of proline dehydrogenase, an important cancer-preventing enzyme in the human body, and analyzed how it works. A paper detailing their results was published today in the Journal of Biological Chemistry.

Parkinson's disease is well-known for its progression of motor disorders: stiffness, slowness, tremors, difficulties walking and talking. Less well known is that Parkinson's shares other symptoms with narcolepsy, a sleep disorder characterized by sudden and uncontrollable episodes of deep sleep, severe fatigue and general sleep disorder.

Investigators at St. Jude Children's Research Hospital have discovered inherited variations in certain genes that make children with acute lymphoblastic leukemia (ALL) susceptible to the toxic side effects caused by chemotherapy medications. The researchers showed that these variations, called polymorphisms, occur in specific genes known to influence pharmacodynamics (how drugs work in the body and how much drug is needed to have its intended effect).

A study released today provides some of the first solid evidence that warming-induced changes in ocean circulation at the end of the last Ice Age caused vast quantities of ancient carbon dioxide to belch from the deep sea into the atmosphere. Scientists believe the carbon dioxide (CO2) releases helped propel the world into further warming. The study, done by researchers at the University of Colorado, Kent State University and Columbia University's Lamont-Doherty Earth Observatory, appears in the May 10 advance online version of the leading journal Science.

Bats generate a measurably distinct aerodynamic footprint to achieve lift and maneuverability, quite unlike birds and contrary to many of the assumptions that aerodynamicists have used to model animal flight, according to University of Southern California aerospace engineer Geoffrey Spedding.

The researcher, together with a multi-institutional team of scientists, found that bat flight is quite different from bird flight, particularly at very small scales. The team based its findings on new measurements of aerodynamic performance in the wing beats of a small species of bat.

How old are the oldest stars" Using ESO's VLT, astronomers recently measured the age of a star located in our Galaxy. The star, a real fossil, is found to be 13.2 billion years old, not very far from the 13.7 billion years age of the Universe. The star, HE 1523-0901, was clearly born at the dawn of time.

"Surprisingly, it is very hard to pin down the age of a star", the lead author of the paper reporting the results, Anna Frebel, explains.