Scientists have discovered that the malaria parasite Plasmodium vivax is evolving rapidly to adapt to conditions in different geographical locations, in particular to defend itself against widely-used antimalarial drugs. The study, published in Nature Genetics today, provides a foundation for using genomic surveillance to guide effective strategies for malaria control and elimination.

P. vivax is mainly found in Asia and South America, and 2.5 billion people are at risk of infection worldwide. This species of malaria parasite is notoriously difficult to work with and the new study has created one of the largest genomic data sets of this species to date, which is available to all researchers.

Progressive neurodegeneration in Parkinson's disease is linked to toxic accumulation of α-synuclein aggregates in neurons. Although mutations in the gene encoding α-synuclein are associated with inherited forms of Parkinson's disease, the identification of other factors that contribute to α-synuclein aggregation may lead to more effective approaches for slowing disease advancement. In this month's issue of the JCI, a team led by Ted Dawson and Han Seok Ko at Johns Hopkins School of Medicine determined that activation of a protein called c-Abl exacerbates α-synuclein accumulation and the appearance of behavioral hallmarks of Parkinson's disease in mice.

Scientists from the John Innes Centre have analysed the genomes of plants that grow in harsh, serpentine soils to find out how they survive in such conditions. It appears that they have used two strategies: adapting to their environment through natural selection that acted on genetic variants which arose locally, as well as by borrowing useful variants from a related plant growing nearby.

If a plant could choose where it wanted to grow, it probably wouldn't choose serpentine soil.

Derived from serpentinite rocks, serpentine soil is dry, low in nutrients, and typically contains metals like nickel and chromium in concentrations that would be toxic to most species.

Antarctic sea ice is constantly on the move as powerful winds blow it away from the coast and out toward the open ocean. A new study shows how that ice migration may be more important for the global ocean circulation than anyone realized.

Teacher burnout and student stress may be linked, according to a University of British Columbia study.

The study is the first of its kind to examine the connection between teacher burnout and students' cortisol levels, which are a biological indicator of stress.

Researchers collected saliva samples from over 400 elementary school children and tested their cortisol levels. They found that in classrooms in which teachers experienced more burnout, or feelings of emotional exhaustion, students' cortisol levels were elevated. Higher cortisol levels in elementary school children have been linked to learning difficulties as well as mental health problems.

Scientists and doctors in recent decades have made vast leaps in the treatment of cardiac problems - particularly with the development in recent years of so-called "cardiac patches," swaths of engineered heart tissue that can replace heart muscle damaged during a heart attack.

Thanks to the work of Charles Lieber and others, the next leap may be in sight.

The Mark Hyman, Jr. Professor of Chemistry and Chair of the Department of Chemistry and Chemical Biology, Lieber, postdoctoral fellow Xiaochuan Dai and other co-authors of a study that describes the construction of nanoscale electronic scaffolds that can be seeded with cardiac cells to produce a "bionic" cardiac patch. The study is described in a June 27 paper published in Nature Nanotechnology.