One Shake Shack French fry may lead you to eat a whole batch, and don't even get started on the power of Doritos. According to a new study using rats, that high-fat indulgence literally changes the populations of bacteria residing inside the gut and also alters the signaling to the brain.

The result? The brain no longer senses signals for fullness, which can cause overeating--a leading cause of obesity. 

The findings presented this week at the Annual Meeting of the Society for the Study of Ingestive Behavior liken a high fat diet to how a sudden significant shift in temperature might impact the people who live in the affected area: Some people will be fine. Others will become ill.

Each cell in the body contains a whole genome, 3 billion of "letters" known as bases, so the data packed into a few DNA molecules could fill an entire hard drive.

Instead of having one reference genome for study, more and more people are having their DNA sequenced, and that is a truly massive amount of data that will require massive computational and storage capabilities beyond anything previously anticipated, says a new assessment from computational biologists and computer scientists at the University of Illinois and Cold Spring Harbor Laboratory.

It is well established that volcanic eruptions contribute to climate variability but quantifying those impacts has proven challenging due to inconsistencies in historic atmospheric data observed in ice cores and corresponding temperature variations seen in climate proxies such as tree rings.

A new study in Nature resolves those inconsistencies with a new reconstruction of the timing and associated radiative forcing of nearly 300 individual volcanic eruptions extending as far back as the early Roman period.

A mutation found in most melanomas rewires cancer cells' metabolism, making them dependent on a ketogenesis enzyme, researchers at Winship Cancer Institute of Emory University have discovered. The finding points to possible strategies for countering resistance to existing drugs that target the B-raf V600E mutation, or potential alternatives to those drugs. It may also explain why the V600E mutation in particular is so common in melanomas.

The growth-promoting V600E mutation in the gene B-raf is present in most melanomas, and also in some cases of colon and thyroid cancer. Drugs such as vemurafenib are available that target this mutation, but in clinical trials, after a period of apparent remission, cancers carrying the V600E mutation invariably develop drug resistance.

Bringing reusable bags to the grocery store brings self-identification as an environmentally friendly shopper, but it also influences the things you buy, according to a new paper in the Journal of Marketing.

Reusable bags were correlated to organic food - no surprise there - but also junk food. 

Think you're a foodie? Adventurous eaters, known as "foodies," are often associated with indulgence and excess. However, a new Cornell Food and Brand Lab study shows just the opposite -adventurous eaters weigh less and may be healthier than their less-adventurous counterparts.