In a new paper,  researchers assess the complete landscape of a cancer's kinome expression and determine which kinases are acting up in a particular tumor.  Since the proteins are relatively easy to target with drugs and plenty of kinase inhibitors already exist, the work shows that those particular kinases can be targeted with drugs and can even lead to potentially combining multiple drugs to target multiple kinases. 

The researchers looked at RNA sequencing data from 482 samples of both cancerous and non-cancerous tissue and identified the most highly expressed kinases in individual breast cancer and pancreatic cancer samples. They found certain common themes.

Messier 106 looks like lots of other galaxies yet it hides a number of secrets. But now, it has slightly fewer than before, thanks to citizen science astronomers.

Scientists have created single layers of a naturally occurring rare mineral called tungstenite, or WS2, and the resulting sheet of stacked sulfur and tungsten atoms forms a honeycomb pattern of triangles that have been shown to have unusual light-emitting (photoluminescent) properties.

 According to Mauricio Terrones, a professor of physics and of materials science and engineering at Penn State, the triangular structures have potential applications in optical technology; for example, for use in light detectors and lasers. 

You don't see many really old, obese people whereas you see a lot of old thin people. It is reasonable to assume, exceptions aside, that obesity kills. 

Unless you reach a certain age, it has been said. When it comes to seniors, research has reported an "obesity paradox" concluding that, at age 65 and older, having an elevated BMI won't shorten your lifespan, and may even extend it. A new study took another look at the numbers, finding the earlier research flawed. The paradox was a mirage: As obese Americans grow older, in fact, their risk of death climbs.

Most mammals, including humans, see in stereo and hear in stereo but the idea that mammals can also smell in stereo has been suspect.

A new study has found that the common mole (Scalopus aquaticus) relies on stereo sniffing to locate its prey. So there is at least one mammal that can, the researcher concludes.

How, when and where a pathogen is transmitted between two individuals in a population is crucial in understanding and predicting how a disease will spread and a new model seeks to lay the foundation for new zoonotic disease spread thinking

By outlining a predictive model of a spatial epidemic spread in a population of territorial animals and quantifying the instances of transmission events, the research team determined the propagation speed of a pathogen using parameters based on the knowledge of the demography of a species, the way animals wander and the degree of contagiousness of the disease.